China Avanafi 330784-47-9//Piracetam Hydrazide 59776-89-5//Algestone Acetophenide CAS 24356-94-3//Ambroxol HCl CAS 23828-92-4//CAS 25122-46-7 Clobetasol Propionate, Find details about China CAS 330784-47-9, Avanafi from Avanafi 330784-47-9//Piracetam Hydrazide 59776-89-5//Algestone Acetophenide CAS 24356-94-3//Ambroxol HCl CAS 23828-92-4//CAS 25122-46-7 Clobetasol Propionate
Introduction
Product Name | Clobetasol Propionate |
Appearance | white powder |
CAS | 25122-46-7 |
Other Name | Clobetasolprop |
Grade | Medicine & Feed & Food |
Assay | 99%min |
Standard | USP31,CP2010 |
Shelf life | 2 Years |
Application | Pharmaceutical Raw Intermediates |
Color | White |
Function
Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic and anti-drug more effective than pred, and promoting the removal of potassium sodium retention is very light, intramuscular or intravenous pituitary - adrenal strong inhibition:
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
Specification
Item | Specification | Results |
Appearance | white to cream,crystalline powder | White crystalline powder |
Identification (by IR) | Confirms to the CRS spectrum | Confirm |
Melting point | Approximately 196ºC | 196ºC |
Specific rotation | +98°~+104°(dried substance) | +78.0° |
Loss on drying | ≤ 2.0% | 0.2% |
Residue on ignition | ≤0.1% | 0.04% |
Heavy metals | ≤20ppm | Confirm |
Related substances(by HPLC) | Any impurity≤1.0% Total impurities≤2.5% | 0.15% 0.15% |
Assay(by HPLC) | Contains 97.0% to 102.0% of C25H32ClFO5 Calculated on dried basis | 100.4% |
Residual solvents | Ethanol ≤ 3000ppm Aceton ≤ 500ppm Pyridi ≤ 100ppm N,N-Dimethylforma ≤ 100ppm | 269ppm <4ppm <3ppm <10ppm |