Fexofenadine Hydrochloride 153439-40-8 High Quality and Competitive Price
China Fexofenadine Hydrochloride 153439-40-8 High Quality and Competitive Price, Find details about China Fexofenadine Hydrochloride, Fexofenadine Hydrochloride Powder from Fexofenadine Hydrochloride 153439-40-8 High Quality and Competitive Price
Basic Info.
Model NO.
Frazer-Fexofenadine Hydrochloride
Appearance
White Powder
Shelf Life
2 Years
Storage
Keep in Cool and Dry Place
Delivery
Express 5-7 Days Arrive
Test Method
HPLC
Assay
99%
MOQ
1kg
Shipping Area
Worldwide/All Countries
CAS
153439-40-8
Mf
C32h40clno4
MW
538.12
Trademark
Xi′an Frazer Biotech Co., Ltd.
Transport Package
Foil Bag
Specification
99%
Origin
China
Model NO.
Frazer-Fexofenadine Hydrochloride
Appearance
White Powder
Shelf Life
2 Years
Storage
Keep in Cool and Dry Place
Delivery
Express 5-7 Days Arrive
Test Method
HPLC
Assay
99%
MOQ
1kg
Shipping Area
Worldwide/All Countries
CAS
153439-40-8
Mf
C32h40clno4
MW
538.12
Trademark
Xi′an Frazer Biotech Co., Ltd.
Transport Package
Foil Bag
Specification
99%
Origin
China
Product Desciption
Fexofenadine Hydrochloride 153439-40-8 High Quality and Competitive Price
Specification of Analysis
Description
Fexofenadine hydrochloride belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.
Medical uses:
Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of chronic urticaria. It does not cure but rather prevents the aggravation of allergic rhinitis and chronic idiopathic urticaria and reduces the severity of the symptoms associated with those conditions, providing relief from repeated sneezing, runny nose, itchy eyes and general body fatigue.
TEST ITEM | SPECIFICATION | RESULTS |
Appearance | White or almost white micro-crystalline powder | White powder |
Solubility | Insoluble in the water and methanol | Complies |
Identification | By IR, to match with the standard. | Complies |
The retention time of major peak of the sample solution corresponds to the standard | Complies | |
Related substance | Individual impurity: Not more than0.1% | 0.03% |
Total impurities: Not more than 0.5% | 0.08% | |
Residue on ignation | Not more than 0.2% | 0.01% |
Loss on drying | Not more than 1.0% | 0.15% |
Heavy metal | Not more than 20ppm | < 20ppm |
Assay (on anhydrous basis) | 98%-101% | 99.78% |
Description
Fexofenadine hydrochloride belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.
Medical uses:
Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of chronic urticaria. It does not cure but rather prevents the aggravation of allergic rhinitis and chronic idiopathic urticaria and reduces the severity of the symptoms associated with those conditions, providing relief from repeated sneezing, runny nose, itchy eyes and general body fatigue.
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