Common Name

Flufenoxuron

 

 

IUPAC

1-[4-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-2-fluorophenyl]-3-(2,6-difluorobenzoyl)urea

 

CAS

N-[[[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl]amino]carbonyl]-2,6-difluorobenzamide

 

CAS No.

101463-69-8

 

Molecular Formula

C₂₁H₁₁ClF₆N₂O₃

 

 

Category

Insecticides > Insect growth regulators
Acaricides / Miticides > Mite growth regulators

 

Activity

Insecticide/Acaricide/Miticide

 

 

Physical Properties

Molecular weight:488.8; Physical form:Tech. is a white, crystalline solid. Density:1.57 kg/l (20 °C) (typical value); Composition:Tech. grade is 98-100% pure. Melting point:169-172 °C ( decomp.); Flash point:Not autoflammable; no explosive properties; Vapour pressure:6.52 ×10-9 mPa (20 °C); Partition coefficient(n-octanol and water):logP = 4.0 ( pH 7); Solubility:In water 7 ×10-11 g/l ( pH 7, 15 °C), 4 μg/l (25 °C). In acetone 82, xylene 6, dichloromethane 24 (all in g/l, 25 °C).; Stability:Stable 190 °C; to natural sunlight; thin film on glass stable >100 h in simulated sunlight. DT50 11 d (ambient in water). On hydrolysis (25 °C), DT50 206 d ( pH 5)

 

Toxicology

Oral:Acute oral LD₅₀ for rats >3000 mg tech./ kg. Percutaneous:Acute percutaneous LD₅₀ for rats and mice >2000 mg/kg. Non-irritating to eyes and skin (rabbits). Inhalation: LC₅₀ (4 h) for rats 5 mg/l air. Phytotoxicity:None recorded. ADI:0.011 mg/ kg b.w. (Bayer 1996).

 

Environmental Profile

Ecotoxicology: 
Birds:Acute oral LD₅₀ for bobwhite quail >2000 mg/ kg.Fish: LC₅₀ (96 h) for rainbow trout >100 mg/l.Other beneficial spp.:Low hazard to predatory mites and other predatory and parasitic arthropods. 

Environmental fate: 
Soil:Strongly adsorbed in soil, DT₅₀ 42 d (clay loam). Use in orchards over 3 years at a dose of 97.5 g/ ha gave rise to low residues in soil which did not significantly affect soil organisms, including earthworms

 

Transport Information

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)