China Factory Supply Hydroxyzine Hydrochloride Powder Hydroxyzine HCl, Find details about China Hydroxyzine Hydrochloride, Hydroxyzine HCl from Factory Supply Hydroxyzine Hydrochloride Powder Hydroxyzine HCl
Factory Supply Hydroxyzine Hydrochloride Powder Hydroxyzine hcl
Product Name | Product Name: Hydroxyzine hcl |
Mini Order: | 1kg |
Purity: | >99% |
Appearance: | White powder |
CAS No. | 2912-20-3 |
Packing: | Select best ways according to quantity and safety degree,professional and experienced. |
Shipping time: | 3-7 working days (Door-to-Door) |
After-sale service: | 24/7 Online for any problems |
Hydroxyzine Dihydrochloride is a histamine H1-receptor antagonist.Target: Histamine H1-ReceptorHydroxyzine inhibits carbachol (10 μM)-induced serotonin release by 34% at 10 μM, by 25% 1 μM and by 17% 0.1 μM in pretreated bladder slices for 60 min [1]. Hydroxyzine (0.1 mM) treatment inhibits the progression and severity of EAE by 50% and the extent of mast cell degranulation by 70% in Lewis rats with allergic encephalomyelitis (EAE) [2]. Hydroxyzine (500 M) significantly increases transport of etoposide to the serosal site in the jejunal everted sacs. Hydroxyzine significantly reduces the efflux and approximately 2.4 g/mL of etoposide in the jejunum and ileum. Hydroxyzine (0.2 μg/mL) significantly enhances the efflux of RH123 to the lumen [3].Hydroxyzine (500 μM) significantly decreases the steady-state etoposide concentration 2-fold, where the steady-state concentration reached about 0.055 μM/mL in Sprague-Dawley rats [3].
Hydroxyzine dihydrochloride is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite cetirizine, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Items | Specification | Results |
Apperance | White or almost white crystalline Powder | Off-White Crystalline Powder |
Identification A | Infrared absorption as stipulation | Complies |
Identification B | Ultraviolet absorption as stipulation | Complies |
Identification C | Presence of chloride as stipulation | Complies |
Melting Point | About 200°C, with decomposition | About 200°C |
Loss on drying (1g, 105°) | ≤5.0% | 1.31% |
Residue on Ignition | ≤0.5% | 0.02% |
Heavy Metals | ≤20ppm | <20ppm |
Any impurities | ≤0.3% | 0.22% |
Total impurites | ≤1.5% | 0.37% |
Assay (On dried Basis) | 98.0% to 100.5% | 99.4% |
Conclusion | The item confirm with USP30 Standard. |
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
1.Are you a manufacturer or trade company?
We are a professional manufacturer.
2.What's our payment terms?
Standard terms: T/T in advance and Western Union. Also L/C at sight is acceptable for large amount.
3. What's your shipping time?
We have a large stock, which means we can deliver the goods to you immediately.
4.How do you ensure the quality of your products?
Strict QC with 6 steps testing from raw material purchase to finished product.
5.How do you ship the order normally?
For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.
6.What's your loading port?
Usually Shanghai, Qingdao, Tianjin, Guangzhou