China Pharmaceutical Intermediate Type a/Type Ab Cimetidine CAS 51481-61-9, Find details about China CAS 51481-61-9, 51481-61-9 from Pharmaceutical Intermediate Type a/Type Ab Cimetidine CAS 51481-61-9
Cimetidine is an immunomodulator and a histamine congener. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent. Cimetidine is an activator of Nischarin.
Item | Standard | Result |
Appearance | White or off-white crystalline powder odorless, bitter taste | Conforms |
IR Absorption | Consist with the spectra obtained with Cimetidine CRS. | Conforms |
UV Absorption | Should conform | Conforms |
Melting point | 139-144°C | 140.5-141.0°C |
Heavy metal | ≤20ppm | <20ppm |
Residue on ignition | ≤0.2% | 0.02% |
Related substances | Single impurity≤0.2% | 0.15% |
Total impurity≤1.0% | 0.47% | |
Loss on drying | ≤1.0% | 0.06% |
Organic volatile impurities (ethanol) (loss on drying) | ≤0.5% | 0.06% |
Assay (calculated with reference on dried substance) | 98.0-102.0% | 99.60% |
Cimetidine (INN) is a histamine H2 receptor antagonist that inhibits stomach acid production. It is largely used in the treatment of heartburn and peptic ulcers.
Packaging: 25kg drum.
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