Cosmetic Product Raw Material Kojic Acid CAS 501-30-4


Kojic acid Basic information

Kojic acid Chemical Properties

Kojic acid Chemical Properties
White Crystalline Solid



Kojic acid Usage
Used in cosmetics, food additives, pharmaceutical etc,Used for quantitative analysis of ferric iron reagent.



Kojic acid  Fuction
1.kojic acid is widely used in food production. In the pas, because of oxidation resistance, it has been used for kojic acid grease to prevent rancidity. Recent reports, kojic acid has sterilization and insect resistance, as food preservatives, preservatives, color protection agent has obvious effect, can replace chemical preservatives, which is widely used in meat dish processing color, fresh fruits and vegetables, antiseptic raw food, but also can be used as cut flowers preservation and conservation agent to extend shelf life. Kojic acid is added in the food, do not influence the taste, aroma and texture and hinder the conversion of nitrite in paired human carcinogenic nitrosamines, which hinder or inhibition of cured meat products upgrading has a very important significance. Agricultural production, kojic acid can be used as biological pesticide, used as an insecticide, and can be used as bio fertilizer, regardless of the spraying or root application, the yield of grain and vegetables income effect is remarkable.
2. as a food flavoring agent of maltol and ethyl maltol raw materials.
3.kojic acid can be used to produce cephalosporin antibiotic raw materials.
4.In addition that kojic acid is widely used in food processing, but also has good freckle, whitening beauty effect. Kojic acid and its derivatives such as acetate has certain antibacterial and on the skin without a one-time stimulus and cumulative irritation, can be used as a preservative in cosmetics and food. Can strongly absorb ultraviolet light, used lonely or compatibility with all kinds of sunscreen products such as soap and so on. Treatment and prevention and treatment of skin pigmentation such as the formation of chloasma, dosage of 1~2.5% effect is obvious. It helps to keep moisture, reduce skin wrinkles. In activities ,it can be with dandruff remover.
5. It can be used for seasoning and manufacturing raw materials of kojic acid and ethyl maltol leaves skin pigment.




Kojic acid  Application 
Kojic acid which is in food, cosmetics, medicine and other aspects for the efficient application, determines its considerable economic value and great potential for development. For industrialized production of kojic acid, Japan has occupied a leading position, but with the development of society, the progress of science and technology, all the countries in the world in terms of kojic acid production have been corresponding development. These provide a broad space for the development of domestic kojic acid industry .
In short, kojic acid faces new opportunities and challenges as a new food additives in 21st century . Kojic acid is as a new type of preservative and will play an important role in food, cosmetic and pharmaceutical industry .


Kojic acid Uses
1.    A nonsteroidal estrogen antagonist of interest in the treatment of some forms of breast cancer. Tamoxife is a Protein Kinase C inhibitor, and induces apoptosis in human malignant glioma cell lines
2.     Tamoxife is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxife is a prodrug that is metabolized to active metabolites 4-hydroxytamoxife (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxife against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxife and its metabolite 4-hydroxytamoxife are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated production in breast tumor cells.
3.      Tamoxife has been used to facilitate the recombination of ect2flox allele in mouse organs91. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation92.






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