China Pharmaceutical Grade Antifungal Raw Material CAS 86386-73-4 Fluconazole, Find details about China Fluconazole, Fluconazole Powder from Pharmaceutical Grade Antifungal Raw Material CAS 86386-73-4 Fluconazole
Name | Fluconazole |
CAS NO. | 86386 -73-4 |
Molecular formula | C13H12F2N6O |
Assay | 99% |
Characteristic | White crystalline powder |
Molecular weight | 306.27 |
Item | Specification |
Appearance | white crystalline powder |
Identification | UV Conforms |
IR Conforms | |
Related substance | Impurity A: ≤0.2% |
Impurity B ≤0.10% | |
Impurity C: ≤0.2% | |
Any other impurity:≤0.10% | |
Total of other impurities:≤0.3% | |
Total impurities:≤1.5% | |
Loss on drying,% | ≤ 0.5% |
Residue on ignition | ≤ 0.1% |
Appearance of solubility | Conforms |
Assay(on dried basis) | 99.00% to 102.00% |
Fluconazole is indicated for the treatment and prophylaxis of fungal infections where other antifungals have failed or are not tolerated (e.g., due to adverse effects), including:
Candidiasis caused by susceptible strains of Candida Tinea corporis, tinea cruris or tinea pedis,Onychomycosis, Cryptococcal meningitis
Fluconazole can be used first-line for the following indications:
Coccidioidomycosis,Cryptococcosis,Histoplasmosis,Prophylaxis of candidiasis in immunocompromised people,
Auto-brewery syndrome
Fluconazole is active against:
Blastomyces dermatitidis,Candida spp. (except C. krusei and C. glabrata),Coccidioides immitis,Cryptococcus neoformans
Epidermophyton spp,Histoplasma capsulatum,Microsporum spp,Trichophyton spp.
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