Beta-NADH disodium salt/beta-Nicotinamide adenine dinucleotide disodium salt CAS 606-68-8

 

 
β-NAD

Formula: C21H27N7O14P2

Molecular Weight: Mr=663.4

CAS No.: 53-84-9

Synonymd: NAD; NAD; DPN; DPN; Oxidized coenzyme-I, Diphosphopyridine nucleotide, oxidized form

Application: API, Intermediate, Diagnostic kit, Health care products, Cosmetic products.etc

Purity: > 98% 

Moisture:<8%

Appearance: White to yellowish powder

Solubility: (c=200mg/ml)Clear, colorless to yellowish solution in water

PH value in water: Approximately 3.0 (c=50mg/ml)

Heavy metal(as Pb): No more than 20ppm

Stability: Stable at +2 to +8 C 

Storage: 

Keep in dry and refrigerated place and protected from light. For prolonged storage keep below -20C

 Why is NAD+ so important?

NAD+ enables cells to generate cellular energy from the food that we eat. It is also an important substrate for a variety of NAD+-consuming enzymes (including PARPs and sirtuins). Even though scientists have known about this molecule for more than 100 years, there are more studies being published on NAD+ than ever before. This resurgence of scientific interest is partly sparked by research showing NAD+ can decrease over time and under metabolic stress. Some scientists even think that declining NAD+ levels may play a major role in the aging process.

In 1906, nicotinamide adenine dinucleotide (NAD+) was discovered as an important coenzyme in human body, and the relationship between NAD+ level and aging has been continuously clarified in the past century [1,2]. In 2007, NAD+ direct precursor nicotinamide RIbose (NR) was officially launched as the "elixir of life" [3]. In 2013, another direct precursor of NAD+, nicotinamide mono-nucleotide (NMN), was also discovered by the "star producer" geneticist David A. Sinclair

Why boost NAD+?

NAD has been shown to decline with age and metabolic stress. It has also been demonstrated to help support many aspects of healthy aging:

• Increases cellular metabolism and energy production
• Maintains healthy mitochondria
• Promotes cellular repair

NMN Published Research 

* Reverse Aging 
*Acticating longevity protein of Sirtuin 1~7
* Increase NAD+ leave
* Activate the immune system 
*Protection of Cardiovascular and Cerebrovascular
*Protect brain neurons

 

Introduction of Beta-Nicotinamide Adenine Dinucleotide disodium salt:

One of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Occurs in 2 forms, α-NAD and β-NAD, distinguished by the configuration of the ribosyl nicotinamide linkage. Only the β-anomer is bioactive.

 

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