China Wuhan Hhd Calcifediol CAS 63283-36-3/19356-17-3 High Quality Vitamin D Derivative, Find details about China Calcifediol, CAS 63283-36-3/19356-17-3 from Wuhan Hhd Calcifediol CAS 63283-36-3/19356-17-3 High Quality Vitamin D Derivative
What is Vitamin D Derivative Drugs?
Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.Calcidiol is a prohormone obtained by hydroxylation of vitamin D3 in the liver.
Basic Information
Product Name: | Calcifediol |
Synonyms: | Calcifediol monohydrate (25-Hydroxyvitamin D3;Calcifediol /25-Dihydroxyvitamin D3;25-OH-VD3;Calcifediol/25-Hydroxycholecalciferol H20;CALCIDIOL;CALCIFEDIOL;CALCIFEDIOL MONOHYDRATE;25-OH-D3 |
CAS: | 63283-36-3 / 19356-17-3 |
MF: | C27H44O2 |
MW: | 400.64 |
EINECS: | 621-370-5 |
Product Categories: | Calcidiol, Didrogyl, Hidroferol |
Quality Standard: | USP41 |
Molecular Structure: | ![]() |
Fp | 14ºC |
Storage temp. | −20°C |
Solubility | Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils. |
Form | Neat |
Uses
Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of ricket.
Treatment of various chronic bone disorders, and metabolic bone disease associated with chronic renal failure, hypocalcemia.
Osteosized diol can promote the absorption of Ca2 +, pi in the small intestine, increase the concentration of serum Ca2 +, pi, reduce the levels of alkaline phosphatase and parathyroid hormone in some patients, and reduce the mineral deficiency of some patients. Treatment and prevention of metabolic bone disease and kidney disease, renal dialysis in patients with chronic renal failure hypocalcemia, lack of rickets, various types of male rickets, osteoporosis, anticonvulsants caused by bone Loose and so have a good effect.
Only for Research & Lab Use,not for human use.
We also supply the following small molecule chemical compounds as follows: