Pharmaceutical Grade API 99% CAS No 2387-59-9 99% Powder S-Carboxymethyl-L-Cysteine
China Pharmaceutical Grade API 99% CAS No 2387-59-9 99% Powder S-Carboxymethyl-L-Cysteine, Find details about China S-Carboxymethyl-L-Cysteine, 2387-59-9 from Pharmaceutical Grade API 99% CAS No 2387-59-9 99% Powder S-Carboxymethyl-L-Cysteine
| Product Name: | S-Carboxymethyl-L-cysteine |
| Synonyms: | Broncodeterge;carbocistein;mucodyne;S-CARBOXYMETHYL-L-CYSTEINE;2-amino-3-(carboxymethylthio)propionic acid;2-azanyl-3-(carboxymethylsulfanyl)propanoic acid;S-Carboxymethyl-L-cysteine USP/EP/BP |
| CAS: | 2387-59-9 |
| MF: | C5H9NO4S |
| MW: | 179.19 |
| EINECS: | 246-934-4 |
It can be used in the curing of chronic tracheitis, emphysema, pulmonary.
- High quality Vorinostat with best price CAS NO.149647-78-9
Product Name: Vorinostat Synonyms: CS-1949;SAHA cpd;UNII-58IFB293JI;Vornostat;Octanediamide, N1-hydroxy-N8-phenyl-;SAHA=N-Hydroxy-N'-phenyloctanediamide;SAHA, N-Hydroxy-Nphenyloctanediamide, Zolinza;Zolinza (See Suberoylanilide Hydroxamic Acid) CAS: 149647-78-9 MF: C14H20N2O3 MW: 264.32 EINECS: 682-505-1
Description
Vorinostat is the first drug in a new class of anti-cancer agents that inhibit histone deacetylases (HDAC). It was launched as an oral treatment for cutaneous manifestations in patients with cutaneous T-cell lymphoma (CTCL) who have progressive, persistent, or recurrent disease on or following two systemic therapies. HDACs are enzymes that catalyze the removal of the acetyl modification on lysine residues of proteins, including the core nucleosomal histones. Together with their counterpart histone acetyltransferases (HATs), HDACs regulate the acetylation level of the histones, which plays an important role in the regulation of chromatin plasticity and gene transcription. Hypoacetylation of histones is associated with a condensed chromatin structure resulting in the repression of gene transcription, whereas acetylated histones are associated with a more open chromatin structure and activation of transcription. In some cancer cells, there is an overexpression of HDACs, resulting in hypoacetylation of histones. Inhibitors of HDAC are thought to transcriptionally reactivate dormant tumor-suppressor genes by allowing for the accumulation of acetyl groups on histones and an open chromatin structure. Vorinostat inhibits the enzymatic activity of HDAC1, HDAC2, HDAC3, and HDAC6 at nanomolar concentrations (IC50 <86 nM). In vitro, it induces growth arrest, differentiation or apoptosis in a variety of tumor cells. In addition, vorinostat inhibits tumor growth in animal models bearing solid tumors, including breast, prostate, lung and gastric cancers, as well as hematologic malignancies such as multiple myeloma and leukemias.
Application
A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic
activity by interfering with signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
antineoplastic, histone deacetylase inhibitor
Packaging Details
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Port:TIANJIN
Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
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