CAS 81103 -11-9 USP 38 Clarithromycin

China CAS 81103-11-9 USP 38 Clarithromycin, Find details about China Clarithromycin Powder, Clarithromycin from CAS 81103-11-9 USP 38 Clarithromycin

Model NO.
Clarithromycin
MW
747.96
Melting Point
217-220°c
Heavy Metals
≤20ppm
Grade
Pharmaceutical
Trademark
HNB
Transport Package
1kg/Bag, 25kg/Drum
Specification
Clarithromycin
Origin
China
Model NO.
Clarithromycin
MW
747.96
Melting Point
217-220°c
Heavy Metals
≤20ppm
Grade
Pharmaceutical
Trademark
HNB
Transport Package
1kg/Bag, 25kg/Drum
Specification
Clarithromycin
Origin
China
CAS 81103-11-9 USP 38 Clarithromycin
 
Item nameClarithromycin
Synonyms6-O-Methylerythromycin
Molecular FormulaC38H69NO13
Molecular weight747.96
CAS No.81103-11-9
Melting point217-220ºC
Appearancewhite
 

Clarithromycin, sold under the brand name Biaxin, is an antibiotic used to treat various bacterial infections.This includes strep throat, pneumonia, skin infections, H. pylori infection, and Lyme disease, among others. Clarithromycin can be taken by mouth as a pill or liquid.

Common side effects include nausea, vomiting, headaches, and diarrhea. Severe allergic reactions are rare. Liver problems have been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by decreasing protein production of some bacteria.


CAS 81103-11-9 USP 38 Clarithromycin
CAS 81103-11-9 USP 38 Clarithromycin
ItemsSpecificationsResults
AppearanceWhite to almost white crystalline powderwhite crystalline powder
SolubilitySoluble in acetone;slightly soluble in dehydrated 
alcohol,in methanol,
and in acctonitrile,and in phosphate 
butter at PH values of 2 to5;
practically insoluble in water
Conforms
IdentificationIR:conforms to the spectrum of clarithromycin RSConforms
Specific optical  rotation-94.--102.(anhydrous substance,1
0mg/ml methylene chloride)
 
-98.
Sulphated ash≤ 0.2%<0.01%
Appearance of solutionClear or not more opalescent than reference 
suspension II and not more intensely coloured than 
reference solutionY7 
Conforms
Crystallinity Meet the requirementsConforms 
pH8.0-10.08.7
Water ≤ 2.0%0.35%
Related substances(1)any single impurity≤ 1.0%0.65%
(2)any impurities
 greater than 0.4%
 
not more than 4 impurities1
(3)total impurities≤ 3.5%2.0%
Heavy metals≤ 0.002%2.0%
Residul solvents     Ethanol ≤ 5000ppm
 
Not detected
Pyridine≤220ppmNot detected
Assay (on dried basis )96.0% ~ 102.0%(anhydrous substance)97.3%
ConclusionIt complies with USP38 standard.



CAS 81103-11-9 USP 38 ClarithromycinCAS 81103-11-9 USP 38 Clarithromycin
CAS 81103-11-9 USP 38 Clarithromycin


CAS 81103-11-9 USP 38 ClarithromycinCAS 81103-11-9 USP 38 ClarithromycinCAS 81103-11-9 USP 38 ClarithromycinCAS 81103-11-9 USP 38 ClarithromycinCAS 81103-11-9 USP 38 Clarithromycin