China Nootropic Hydrafinil 9-Fluorenol Powder Purity 99% CAS 1689-64-1, Find details about China 9-Fluorenol, CAS 1689-64-1 from Nootropic Hydrafinil 9-Fluorenol Powder Purity 99% CAS 1689-64-1
Product name | 9-Fluorenol |
CAS number | 1689-64-1 |
Molecular formula | C13H10O |
Molecular weight | 182.22 |
Melting point | 153-154 °C(lit.) |
Boiling point | 275.62°C (rough estimate) |
Density | 1.0368 (rough estimate) |
Appearance | Creamy white powder |
Purity | 99.0% |
Function | Dopamine reuptake inhibitor: An increase in dopamine production is known to improve cognition. Hydrafinil plays a role as a dopamine reuptake inhibitor, increasing dopamine concentrations. 5-HT6 antagonist: Antagonism of 5-HT6 receptor can result to increase in norepinephrine and dopamine concentrations in the prefrontal cortex, as well as increasing the production of choline and glutamate in different parts of the brain. Makers of Hydrafinil theorize that it functions as a 5-HT6 receptor antagonist. Increase Glutamate levels: As mentioned earlier, antagonism of 5-HT6 receptors increases the production of glutamate in the brain. This could lead to enhanced memory and learning process. There is a great possibility that Hydrafinil's function as a 5-HT6 receptor antagonist could result in the improvement of cognitive performance. Increase Norepinephrine levels: Manufacturers of Hydrafinil claim that it increases norepinephrine levels specifically in the prefrontal cortex by antagonizing 5-HT6 receptor. Increase in concentrations of norepinephrine could result to improvement of cognition. However, there's no enough evidence to prove this theory. Increase Histamine levels: Hydrafinil is known to enhance histamine levels in the hypothalamus. Histamine plays an important role in normalizing our circadian rhythm and regulating sleep-wake cycles. |
Discribe | Hydrafinil (or 9-Fluorenol) is a wakefulness-promoting agent, countering sleepiness and inattention. It's an analogue and pro-drug of (also known as Provigil) - a compound used by Airforce pilots on long missions to stay awake and alert. Hydrafinil (aka 9-Fluorenol) is a novel eugeroic nootropic that is very similar in action to. It was originally developed as a research compound to promote wakefulness and alertness. Due to its reported efficacy as a eugeroic agent, it is becoming popular among advanced nootropics users. Interestingly, users report less stimulating effects than , but a greater ability to promote vigilance. Other reported benefits include attentional enhancement, increased motivation, subtle mood boost, improved cognitive function and ability to learn. Fluorenol is an alcohol derivative of fluorene and is being clasisfied as a eugeroic compound, promoting wakefulness. The company Cephalon investigated Fluorenol in comparison to the popular eugeroic drug modafinil. In their comparison research with rodents, they noted that Fluorenol was significantly more effective than (up to 39%). Although it has dopamine reuptake properties, they tend to be pretty weak. Fluorenol is an alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. Hydroxyfluorene can be converted to fluorenone by oxidation. It is a white-cream colored solid at room temperature. |