China Northwest Factory Manufacturer Act-129968 CAS 866460-33-5 Setipiprant for Stock Delivery, Find details about China Setipiprant, Act-129968 from China Northwest Factory Manufacturer Act-129968 CAS 866460-33-5 Setipiprant for Stock Delivery
Hair Loss Treatment High Quality Pure 99% Purity Powder CAS 866460-33-5 Setipiprant
Product Name | Setipiprant |
CAS NO. | 866460-33-5 |
Molecular Formula | C24H19FN2O3 |
Assay | 99% |
Grade Standard | Medicine Grade |
Storage | Cold Dry Place |
Shelf life | 2 Years Properly Stored |
1. Increase cellular proliferation of outer root sheeth cells.
2. Increase hair diameter and hair density.
3. Increase the percentage of hair in the anagen phase.
4. Exert no negative effect on body hormone levels.
5. Provide equivalent or better net growth than Finasteride.
Setipipran is an oral drug that's currently being tested for use as a hair loss treatment. It was initially developed as a treatment for allergic rhinitis, but recent hair loss-related discoveries have made it a better candidate for hair loss reversal.
In short, setipiprant is an antagonist of the prostaglandin D2 receptor 2 (DP2). This receptor is responsible for bonding with and responding to certain prostaglandins, particularly PGD2. This prostaglandin has been linked to various pathological responses, including those linked to allergies, asthma, and inflammation.
It's known that PGD2 is produced from PGD2 synthase, an enzyme. And PGD2 synthase levels are increased by - you guessed it! - DHT. With an increase in PGD2, the PGD2 receptor on the scalp is then triggered, which causes inflammation.
According to researchers, setipiprant steps in before PGD2 attaches to the receptors, and therefore prevents receptor activation and, as a result, hair loss.
With the discovery of the possible link to PGD2 receptors, the drug was acquired by Kythera, and trials began to test the effects of setipiprant on hair loss
As setipiprant is believed to interfere with the receptors known to contribute to allergies/allergic responses, the drug was first tested on allergies and asthma.
In clinical trials, the drug performed quite well in the treatment of allergen-induced airway responses in asthmatic patients. It was also well tolerated by participants. However, its results were similar to those of drugs already on the market, so further trials were discontinued.
In 2012, researchers discovered a link between the PGD2 receptor and hair loss. More specifically, this receptor is seen at high levels in the scalps of men diagnosed with Androgenetic Alopecia (AGA).
AGA (Male-Pattern Baldness) is the most common cause of hair loss in men, though it's also seen in women (Female Pattern Hair Loss). It's believed to be caused by a sensitivity to DHT, which is an androgen hormone that attaches to the follicles and leads to inflammation and irritation.
1. Quality: A set of sophisticated equipments and skills, high purity is guaranteed;
Quality has to be perfect.
Quality is life of our buisness, also is your business life, so we will send perfect raw materials to you.
We are looking for long-termed business relationship, not one time buisness. So our company place much emphasis on our products quality.
We can understand the quality worry from our clients, So that product's quality control and customer's satisfaction was the most important part in our management.
We must check the quality of every batch of products beforte sending out to clients .
2.Price: Competitive offer in the Market, and moreover Big Discounts for big orders;
3.Safe: A group of experienced packagers and a set of safe packing ways for your choice; Besides special channel + good packaging ways, Your Supplier needs to know more about your Country Customs, which can decrease your trouble, let's take some examples:
Δ Poland: When you send a parcel with total weight over 2kg they are going with different service and are checked more thorough .
ΔΔ Switzerland: We must have experience in properly declare the package because that is Switzerland is very hard .if the package were worth more than 20 euros and then our friends have to pay customs , moreover it means the Customs Staff opens the package .
ΔΔΔ Norway: It is illegal to import any product to Norway that contains meat or milk, and we need to set the value on the order to under 35 dollars. Otherwise our friends in Norway have to pay 20% tax.
ΔΔΔΔ Colombia: We need the packages to weigh under 2kg because if it weighs more than 2kg my friend has to go to the post office to pick it up
ΔΔΔΔΔ Australia: There are two Main Customs in Australia: Customs of MELBOURNE VIC and Customs of SYDNEY NSW. As we know the latter one is very easy to pass. Different Courier Choice can make parcels go through different Customs. We will help you choose the shipping Courier which can make sure your parcel go through easy Customs of SYDNEY NSW, and make sure success rate 100%.
ΔΔΔΔΔΔ Spain: Taxes when is here,if the order exceed 20€ the customs apply taxes in spain, so decleard valuse should be controlled under 20€ .
4.Service: Tracking number and your Package photos would be sent to you within 12 hours after receiving payment(Except Sunday, we work from Monday to Saturday).
Q1: Will you supply samples for testing
A: Samples are available for most products.
Q2: What's your MOQ
A: For the high value product, our MOQ starts from 10g or 100g ; For the low value product starts from 1kg.
Q3: Which kind of payment terms do you accept
A: T/T, Western Union , Money Gram and Paypal
Q4: How about your delivery time
A: →You can receive parcel photo from us within 6 hours after receiving your payment;
→You can receive your tracking number within 24 hours after receiving your payment;
→You can receive your parcel in 8 to 16 days .
Q5: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6: I buy a lot of products from China, but I every time I spend much money, time and energy in finding and buying the goods, sometimes poor goods, could you help me handle this if I can be your customer?
we can help clients to buy solvents such as EO, BB, BA, GSO, Guaiacol when you are going to buy them ;
we can help clients to buy 5ml or 10ml vials including rubber stopper, flip off cap in China at factory cost;
we can help clients to buy 13mm or 20mm stainless Vial crimper /Capping tool in China at factory cost;
we can help clients to buy mechanical filter including pump, vacuum filter holder and membrane of 50mm,0.22um;
we can help clients to buy single-punch tablet press Machine in China at factory cost;