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Factory Supply High Quarity Mifepristone CAS 84371-65-3

China Factory Supply High Quarity Mifepristone CAS 84371-65-3, Find details about China Mifepristone, 84371-65-3 from Factory Supply High Quarity Mifepristone CAS 84371-65-3

Model NO.
Mifepristone
Apearance
White Powder
CAS
84371-65-3
Mf
C29h35no2
MW
429.6
Storage
Cool Dry Place
Shelf Life
2 Years
Deliver Time
7-10days
Trademark
Biocar
Transport Package
Bag or Drum
Specification
1kg/Bag; 25kg/Drum
Origin
Guangzhou, Guangdong, China
HS Code
2937290090
Model NO.
Mifepristone
Apearance
White Powder
CAS
84371-65-3
Mf
C29h35no2
MW
429.6
Storage
Cool Dry Place
Shelf Life
2 Years
Deliver Time
7-10days
Trademark
Biocar
Transport Package
Bag or Drum
Specification
1kg/Bag; 25kg/Drum
Origin
Guangzhou, Guangdong, China
HS Code
2937290090
Factory Supply High Quarity Mifepristone CAS 84371-65-3
Factory Supply High Quarity Mifepristone CAS 84371-65-3
Product Details
Factory Supply High Quarity Mifepristone CAS 84371-65-3
Factory Supply High Quarity Mifepristone CAS 84371-65-3
describe

Mifepristone, also known as anti-progesterone, cibrix, cibrix, cytopenol, simiane and minastrone, is a new type of anti-fertility drug that acts on the receptor level and has no activity of progesterone, androgen and estrogen, which was first developed by Roussel-UolSF in France in the early 1980s. It was first marketed in France in 1988. Main role in endometrial progesterone receptor, can compete with progesterone receptor and the glucocorticoid receptor, has high affinity, endometrial progesterone receptor affinity for five times stronger than progesterone, under the effective dose of cortisol Chemicalbook had no obvious effect, can produce a strong resistance to progesterone effect, make the pregnancy decidua and villi tissue degeneration, Endogenous prostaglandin release, leading to uterine contraction, and can reduce the production of human chorionic gonadotropin, luteinysis, so that the embryo abortion. Because this drug can not cause enough uterine activity, the incomplete abortion rate is higher when used only in early pregnancy, but it can increase the sensitivity of uterus to prostaglandin. Therefore, adding small dose of prostaglandin can not only reduce the adverse reactions of prostaglandin, but also significantly increase the complete abortion rate. In addition, mifepristone also has the effect of softening and dilating the cervix
 

Function

Mifepristone has a strong anti-progesterone activity. Animal experiments show that the binding force of mifepristone to progesterone receptor is 3-5 times higher than that of progesterone. Mifepristone mainly acts on the endometrium and competes with endogenous progesterone to bind receptors at the molecular level to produce a strong anti-progesterone effect and produce the following physiological activities:

  1. Competitive occupation of progesterone receptors in the decidua causes the withdrawal of progesterone, denaturation and necrosis of decidua tissues, secondary damage and dissection of villi, decrease of HCG level and dissolution of corpus luteum of Chemicalbook. The mechanism is that mifepristone directly acts on the syncytic cytotrophoblast, resulting in a dosedependent decrease in the production rate of HCG, HPL and P.
  2. promote endogenous prostaglandin release, leading to uterine contraction.
  3. At the same time, it also acts on the anterior hypophysis of the hypothalamus, prompting the decline of FSH and LH and luteinysis, thus making pregnancy failure dependent on luteinization maintenance and leading to abortion.
  4. Acting on the cervix to soften and expand, which is conducive to the discharge of the embryo sac and decidua.

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Factory Supply High Quarity Mifepristone CAS 84371-65-3
About Us
Factory Supply High Quarity Mifepristone CAS 84371-65-3
Factory Supply High Quarity Mifepristone CAS 84371-65-3
Factory Supply High Quarity Mifepristone CAS 84371-65-3Factory Supply High Quarity Mifepristone CAS 84371-65-3Factory Supply High Quarity Mifepristone CAS 84371-65-3Factory Supply High Quarity Mifepristone CAS 84371-65-3
Our Service
1.Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.

FAQ
1.Will you supply samples for test the quality? 
We'd like to offer the samples for the quality evaluation,the shipping cost is borne by customers.
2.What is the payment term? 
T/T, Western Union or L/C and Money Gram and BTC .
3.What is your package?
Powder: PE bag, glass bottle or PTFE bottle for inner packing
Liquid: glass bottle or PTFE bottle for inner packing
Bulk order: Fiber drum or steel drum.
4.What is your delivery term and delivery period? 
FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you.The sample within 5 days, and bulk order within 7 days.
5.How to delivery by express?
A: Parcel will be shipped out in 3 working days after payment. Usually we use EMS, ePacket, Fedex, DHL, TNT and USA Domestic mixed shipping and so on. 
6.Is there a discount?
A: Yes, for larger quantity, we always support with better price. 
7.What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
8.How to make orders?
A: Send inquiry to us,we do the offer. Payment via Western Union, Moneygram, Bank Account ect.. Then we will arrange shipping. After delivery we will offer tracking No.



 

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