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Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2

China Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2, Find details about China Agomelatine, Agomelatine Powder from Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2

Model NO.
138112-76-2
Trademark
Lx
Transport Package
Discreet Package
Specification
Customized
Origin
China
HS Code
3824999999
Model NO.
138112-76-2
Trademark
Lx
Transport Package
Discreet Package
Specification
Customized
Origin
China
HS Code
3824999999
                                     
Description
 

Product name

Agomelatine 

CAS No.

138112-76-2

Molecular Formula

C15H17NO2

Molecular weight

243.30098

Purity

99%

Grade Standard

Medicine Grade

Agomelatine is the world's first melatonin receptor MT1 and MT2 agonist antidepressant. It was developed by the French company Servier and is suitable for the treatment of severe depressive episodes in adult patients. We know that melatonin is an endogenous neurohormone, which is secreted only by the anterior pituitary of the pineal gland at night, and acts on the melatonin receptors concentrated in the suprachiasmatic nucleus (SCN) of the hypothalamus. Participates in mediating the circadian rhythm of mammals. It is a well-known guardian of time in the body and corrects the biological clock regulated by the external circadian cycle. However, due to the high catabolism rate of melatonin in the body, its short half-life and poor selectivity for its receptor located in the SCN have limited its use in the treatment of circadian circadian rhythm disorders. Therefore, in order to overcome these shortcomings of melatonin, the researchers designed a series of melatonin analogs. Molecular model studies show that the indole ring of melatonin is the structural site for catabolism inactivation, so the indole ring becomes an ideal site for isosteric modification. The agomelatine developed by Servier is the biological (electronic) isostere analogue of melatonin. It replaces the indole ring with a nucleus, making it more metabolically stable than melatonin .


 Production Process


Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2
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Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2
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Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2
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Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2
Our Advantages:
 
Anti-Major Depressive Disorder in Adults Raw Materials Agomelatine CAS 138112-76-2
1.We are very experienced with this field(more than 10 years);
2.Good after-sales service
3.100% quality guaranteed;
4.We accept sample order for testing;
5.Strong supply ability
6.Made in China gold members with high credit guarantee.


FAQ
Q1: Can i get some samples?
A: Yes 

Q2:Payments Methods?
A: Payment by Bitcoin,Credit card, T/T, Western Union Etc.

Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to
pay the shipping cost or arrange a courier to us and take the samples.

Q4:What's your MOQ?
A:Our MOQ is 1g. 

Q5: How about delivery leadtime?
A:About 3-5 working days after payment confirmed. 

Q6:Is there a discount?
A:Different quantity has different discount.

Q7: How do you treat quality complaint?
A:We will send you free goods for replacement or refund your loss.

 

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