Pharmaceutical Purity Powder Agomelatine Material Agomelatine Raw Powder Agomelatine
China Pharmaceutical Purity Powder Agomelatine Material Agomelatine Raw Powder Agomelatine, Find details about China Agomelatine, Tablet Agomelatine from Pharmaceutical Purity Powder Agomelatine Material Agomelatine Raw Powder Agomelatine
Basic Info.
Model NO.
D-sung Agomelatine
Product Name
Agomelatine
Name
Agomelatine Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Anti-Depression;Nootropics
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
138112-76-2
Mf
C15h17no2
MW
243.306
Boiling Point
478.8 °c at 760 Mmhg
Density
1.109
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Agomelatine
Product Name
Agomelatine
Name
Agomelatine Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Anti-Depression;Nootropics
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
138112-76-2
Mf
C15h17no2
MW
243.306
Boiling Point
478.8 °c at 760 Mmhg
Density
1.109
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Pharmaceutical Purity Powder Agomelatine Material Agomelatine Raw Powder Agomelatine
| Product name | Agomelatine |
| Cas number | 138112-76-2 |
| Apperance | White powder |
| MF | C15H17NO2 |
| MW | 243.306 |
Agamelatine is a melatonin receptor agonist (MT1 and MT2 receptors) and 5-HT2C receptor antagonist. Animal studies have shown that agomelatine can correct the circadian rhythm in animal models with circadian rhythm disturbance, so that the circadian rhythm can be reconstructed.
Agomelatine has shown antidepressant effects in a variety of animal models of depression.The mechanism of antidepressant may be related to the increase of neuronal plasticity and neuronal proliferation in hippocampus.
Immunostaining was used to measure the proliferation, regeneration and death of nerve cells in the brain of adult rats. It was found that long-term (3 weeks) administration of agomelatine increased the proliferation and regeneration of neurons in the ventral dentate gyrus of the hippocampus, which is involved in emotional response.No similar effect was observed at acute or subacute administration (4 h or 9 weeks).
After prolonged administration, the whole dentate gyrus region showed cell proliferation and neuronal regeneration, suggesting that agomelatine can increase the nerve regeneration in hippocampus to some extent, thus generating new granulosa cells.
1. Agomelatine - Mental Illness Another "blockbuster" class of drugs.
2. Agomelatine has antidepressant, anti-anxiety, adjusting sleep rhythm and regulating the role of the biological clock, and its adverse reactions, sexual performance without adverse effects, and no withdrawal response.
3. Agomelatine has a good effect on patients with depression, and adverse reactions are very small.
Agomelatine has shown antidepressant effects in a variety of animal models of depression.The mechanism of antidepressant may be related to the increase of neuronal plasticity and neuronal proliferation in hippocampus.
Immunostaining was used to measure the proliferation, regeneration and death of nerve cells in the brain of adult rats. It was found that long-term (3 weeks) administration of agomelatine increased the proliferation and regeneration of neurons in the ventral dentate gyrus of the hippocampus, which is involved in emotional response.No similar effect was observed at acute or subacute administration (4 h or 9 weeks).
After prolonged administration, the whole dentate gyrus region showed cell proliferation and neuronal regeneration, suggesting that agomelatine can increase the nerve regeneration in hippocampus to some extent, thus generating new granulosa cells.
1. Agomelatine - Mental Illness Another "blockbuster" class of drugs.2. Agomelatine has antidepressant, anti-anxiety, adjusting sleep rhythm and regulating the role of the biological clock, and its adverse reactions, sexual performance without adverse effects, and no withdrawal response.
3. Agomelatine has a good effect on patients with depression, and adverse reactions are very small.
You Might Also Like
One-Stop Medical Printed Circuit PCB Board PCBA Motherboard ......
Manufacturer En10219 Standard S235jr Square/Rectagular Secti......
0.34~65 Stationary Type Seize Exported Package Customized Ai......
2333210-2 Te Connectivity Automotive Connector 1 POS Vertica......
3 Wheel Motorized Tricycle for Handicapped with Extra Seat
150m3/Hour Dry Land Gold Washing Plant for Sales in R......
Prefabricated Houses Modified Container Hotel Living Villa C......
Home Gym Exercise Equipment Mini Stepper
Bend Wire Mesh Fence
High-Speed Horizontal Servo Labeling Machine (Model: SHL-258......
30W Lithium Battery All in One Solar Lighting Outdoor Solar ......