SU-250
SU-400
TA-300
Test mix 325
TE-300
TE-250
TC-200
TP-100
DECA-300 (ND-300)
TRENMIX-200
DP-100
MAST-200
TrX-100
PRIMO-100
PROVI-100
Blend-500
Blend-375

 

Bodybuilding estrogen's function

• Structural changes (promotion of the growth and development of female secondary sexual characteristics)
• Protein synthesis (increases hepatic production of binding proteins)
• Metabolism (accelerates body's metabolism, burns fat)
• Lipid profile (increases HDL, triglyceride; decreases LDL, fat deposition)
• Fluid balance (salt/sodium, water retention)
• Hormonal (increases growth hoe; increases cortisol, SHBG)

Products Name:Isotretinoin
Brand Name:iPLEDGE
CAS No.: 4759-48-2
Molecular Formula:C20H28O2
Molecular Weight: 300.44g/mol
EINECS No: 225-296-0
Appearance: Yellow crystalline powder
Typical use:  Accutane
Standard Packing : 10gram,100gram,1kg
Shelf Life :2 years
Storage:Room temperature away from light

Describtion:
What is Isotretinoin?
Isotretinoin belongs to the first generation of vitamin A acid. It is a stereoisomer of all-trans vitamin A acid. Oral administration has an anti-oil effect which has special effect on severe acne. The mechanism is as follows:
 
Application:
1. it can reduce sebaceous gland and inhibit the activity of sebaceous gland, reducing the effect of secretion of the sebaceous glands, thus inhibiting the growth of Propionibacterium which relies on lipid environment.
2. it has an anti-keratosis effect, can inhibit the excess proliferation of epidermal and promote its differentiation. It also reduces the keratosis of hair follicles and the catheter of sebaceous glands.
3. it can also affect the function of lymphocytes and monocytes, and inhibit the chemotaxis of neutrophil, and thus having anti-inflammatory activity.
4. it can exert its therapeutic effect by selectively binding Vitamin A acid nuclear receptors. It can inhibit the proliferation of acne rod bacilli. Moreover it has effects of immunity stimulation at low doses, but has immunity suppression effect at high doses.
5. It can inhibit the biogenesis of collagenase and gelatinase in the skin, and can also inhibit the activity of ornithine decarboxylase. Owing to the major role of ornithine decarboxylase in inducing skin mutations, so isotretinoin can also suppress tumorigenesis.
6. when subjects to topical administration, it has a similar mechanism of action as vitamin A acid which induces the proliferation of epidermal cell, promotes the differentiation of epidermal cell granular layer into the stratum corneum. It can also regulate the horny plug occurring during some abnormal cornification processes of Hair follicle sebaceous epithelium, and thus playing a therapeutic role.