China High Quality Medicine Valacyclovir Hydrochloride CAS No. 124832-27-5 with Best Price, Find details about China Valacyclovir Hydrochloride, 124832-27-5 from High Quality Medicine Valacyclovir Hydrochloride CAS No. 124832-27-5 with Best Price
Introduction:
Product Name: Valacyclovir Hydrochloride
Synonym: Valaciclovir HCL
Cas No.: 124832-27-5
Molecular Formula: C13H21ClN6O4
Molecular Weight: 360.8
Valaciclovir is a guanine analogue antiviral, at an STD clinic for the treatment of herpes simplex and herpes zoster infection.It is the first drug acyclovir, which can be converted in vivo to aciclovir.
Valaciclovir Hydrochloride, as a prodrug of acyclovir, can be taken orally and transferred into acyclovir in the body quickly. Its antivirus activity is due to the acyclovir. The drug is phosphorylated into activated acyclovir triphosphate, deoxynucleoside competition virus thymidine kinase or cell kinase, deoxyguanosine triphosphate competition virus DNA polymerase, thus inhibiting virus DNA synthesis to show antivirus activity.
Function:
Treatment of herpes labialis (perioral herpes, cold sores, fever blisters) in adults and adolescents.
Treatment of recurrent mucocutaneous HSV infections in HIV-infected adults.
Application:
Specification:
ITEMS | SPECIFICATION |
APPEARANCE | A WHITE TO OFF-WHITE CRYSTALLINE POWDER |
CHARACTERISTICS | OPTICAL ROTATION : -8.5º- -11.5º |
ABSORPTIVITY (UV): ( E1%1CM)360-390 | |
IDENTIFICATION | 1) POSITIVE |
2) HPLC:CONFORMS TO STANDARD | |
3) IR ABSORPTION:CONFORMS TO STANDARD | |
4) POSITIVE | |
TEST | 1) PH:4.0-6.0 |
2) ACICLOVIR: ≤1.5% | |
3) RELATED SUBSTANCES: ≤2.0% | |
4) LOSS ON DRYING: ≤8.0% | |
5) RESIDUE ON IGNITION: ≤0.1% | |
6) HEAVY METALS: ≤20 PPM | |
ASSAY | ≥98.0% |
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