API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir

China API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir, Find details about China Valacyclovir, Valacyclovir Powder from API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir

Basic Info.

Model NO.

Condavo-Valacyclovir

Name

Valacyclovir

Product Name

Valacyclovir Powder

Appearance

White Powder

Color

White Color

Test Method

HPLC UV

Storage

Cool Dry Place

Shelf Life

2 Years

Assay

99%

CAS

124832-27-5

C13h21cln6o4

360.8

Density

1.55

Melting Point

170-172c

Boiling Point

588.4c at 760 Mmhg

Flash Point

309.7c

Trademark

Condavo

Transport Package

1kg/ Aluminium Bag or 25kg/Drum; as Required

Specification

99%

Origin

Shaanxi

Model NO.

Condavo-Valacyclovir

Name

Valacyclovir

Product Name

Valacyclovir Powder

Appearance

White Powder

Color

White Color

Test Method

HPLC UV

Storage

Cool Dry Place

Shelf Life

2 Years

Assay

99%

CAS

124832-27-5

C13h21cln6o4

360.8

Density

1.55

Melting Point

170-172c

Boiling Point

588.4c at 760 Mmhg

Flash Point

309.7c

Trademark

Condavo

Transport Package

1kg/ Aluminium Bag or 25kg/Drum; as Required

Specification

99%

Origin

Shaanxi

Product Desciption

API Antiviral Valaciclovir powder Valacyclovir Hydrochloride Powder Valacyclovir

API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir

Product Name	Valacyclovir
CAS	124832-27-5
Appearance	White crystalline powder
MF	C13H21ClN6O4
MW	360.8
Purity	99%
Shelf Life	2 Years

Valacyclovir hydrochloride, an orally active L-valyl ester of the potent antiviral agent aciclovir, was launched in 1995 in the United Kingdom for the treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes, including initial and recurrent enital herpes. As a prodrug, valaciclovir has an improved pharmacokinetic profile to aciclovir. It is rapidly absorbed after oral administration and extensively converted to aciclovir via first-pass metabolism to achieve plasma levels of aciclovir comparable to those seen with aciclovir via i.v. route. Valacyclovir is then activated selectively in virus-infected cells by viral thymidine kinase to form aciclovir triphosphate in a stepwise fashion. This active species inhibits viral DNA polymerase via irreversible binding to the active site of the enzyme. Once aciclovir is incorporated into the elongating viral DNA, it terminates replication of the viral DNA strand, an antiviral mechanism unique to aciclovir. Valacyclovir is reportedly in clinical trials for the suppression of cytomegalovirus infection and disease in renal transplant patients.

API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir

API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir Treatment of initial episodes of genital herpes in immunocompetent or HIV-infected adults and adolescents.
Treatment of herpes labialis (perioral herpes, cold sores, fever blisters) in adults and adolescents.
Treatment of recurrent mucocutaneous HSV infections in HIV-infected adults.
API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir

Valaciclovir hydrochloride hydrate is the l-valine ester of acyclovir, which is the body prodrug of acyclovir. Acyclovir is hydrolyzed into acyclovir immediately after entering the body. It is used for the treatment of varicella zoster and herpes simplex virus type I and II infection, including incipient and recurrent genital herpes virus infection.

API Antiviral Valaciclovir Powder Valacyclovir Hydrochloride Powder Valacyclovir