China Best Selling Dyclonine Hydrochloride/Dyclonine HCl Powder CAS 536-43-6, Find details about China Dyclonine Hydrochloride, Dyclonine Hydrochloride Powder from Best Selling Dyclonine Hydrochloride/Dyclonine HCl Powder CAS 536-43-6
Name: Dyclonine hydrochloride |
Synonyms: Dyclonine hcl |
C.A.S NO. : 536-43-6 |
Molecular formula: C18H27NO2.HCl |
Molecule weight: 325.87 |
Specification: HPLC 99% |
Characteristics: White to off white powder |
Melting point: 175-176°C |
Dyclonine hydrochloride (also known as clone hydrochloride, chemical name 4-butoxy-β-piperidinyl propiophenone hydrochloride, is a fast onset, long duration of action, adverse reactions, safety High local anesthetic. Clinical for mucosal surface anesthesia and skin pain, itching.
The main mechanism of action is nerve block, local anesthesia fast, strong pharmacological effects and long duration, small toxicity, analgesic, antipruritic, bactericidal effect.
Item | Specifications | Results |
Appearance | A white crystalline powder | White crystalline powder |
Identification | IR; HPLC | Conforms |
Sulfates | NMT0.05% | Conforms |
Toluene | NMT890ppm | Not detected |
Methanol | NMT3000ppm | Not detected |
Related substances (TLC) | NMT1.0% | Conforms |
Loss on drying | NMT0.5% | 0.07% |
Sulfated ash | NMT0.1% | 0.09% |
Ammonium | NMT0.08% | Conforms |
Heavy metals | NMT0.001% | Conforms |
Microbiology | Total bacterial count:<1000CFU/g | 30CFU/g |
Total Fungus count: <100CFU/g | <10 CFU/g | |
Escherichia coli: Not detected | Not detected |
Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction blockade. This results in a transient and reversible loss of sensation in a localized area of the body.
The main mechanism of action is nerve block, local anesthesia fast, strong pharmacological effects and long duration, small toxicity, analgesic, antipruritic, bactericidal effect.