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Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790 -58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin

China Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin, Find details about China Alpha-Ketoglutaric Acid, CAS 328-50-7 from Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin

Model NO.
Sitagliptin
Colour
White
MW
407.31
Function
Biological and Pharmaceutical Intermediates
Shelf Life
2 Years
Test Method
HPLC UV
Storage
Cool Dry Place
Payment
Tt.Western Union .Credit Card.Moneygram
Delivery Time
Within 2 Days
Certificate
COA MSDS
Sample
Available
MP
114.1-115.7 °c
Bp
529.9±60.0 °c(Predicted)
Trademark
Faithful
Transport Package
Aluminum Foil Bag Packaging
Specification
10g/bag; 100g/bag; 1kg/bag
Origin
China
Model NO.
Sitagliptin
Colour
White
MW
407.31
Function
Biological and Pharmaceutical Intermediates
Shelf Life
2 Years
Test Method
HPLC UV
Storage
Cool Dry Place
Payment
Tt.Western Union .Credit Card.Moneygram
Delivery Time
Within 2 Days
Certificate
COA MSDS
Sample
Available
MP
114.1-115.7 °c
Bp
529.9±60.0 °c(Predicted)
Trademark
Faithful
Transport Package
Aluminum Foil Bag Packaging
Specification
10g/bag; 100g/bag; 1kg/bag
Origin
China
Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-ketoglutaric acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin

Introduction

product NameSitagliptin
Synonyms(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; 1,2,4-Triazolo(4,3-a)pyrazine, 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8-tetrahydor-3-(trifluoromethyl)-; Sitagliptin Intermediate; (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine; (3S)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Molecular FormulaC16H15F6N5O
Molecular Weight407.3136
InChIInChI=1/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m0/s1
CAS Registry Number486460-32-6;790712-60-6
Molecular Structure
 
Density1.614g/cm3
Boiling point529.905°C at 760 mmHg
Refractive index1.59
Flash point274.277°C
Vapour Pressur0mmHg at 25°C

Function

Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
 

Specification

Appearance     

White or almost White powder

White powder

Solubility

Easy to dissolve in the water

Complies

Identification

High -performance liquid chromatograph HPLC

Almost the same

Infrared absorption

Almost the same

Melting point

203.0-205.0ºC

204.0~205.0ºC

Chiral impurity:

≤1.0%

0.4%

 

Related

Impurities:

Total Impurities ≤1.0%

0.63%

Water

≤1.0%

0.6%

Heavy metals

≤20ppm

<20ppm

Residue on ignition

≤0.1%

0.01 %

Specific Rotation

Between -18.0 °and 23.0°

-21.05°

HPLC Assay

98.0% ~  102.0%

99.5%

Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin
Alpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 SitagliptinAlpha-Ketoglutaric Acid CAS 328-50-7//Ambroxide CAS 6790-58-5//6-Methylcoumarin CAS 92-48-8//4-Methylumbelliferone CAS 90-33-5//CAS 486460-32-6 Sitagliptin

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