Top Purity >99% Main Estrogens CAS 50-27-1 Estriol in Treating Multiple Sclerosis

China Top Purity >99% Main Estrogens CAS 50-27-1 Estriol in Treating Multiple Sclerosis, Find details about China Estriol, CAS 50-27-1 from Top Purity >99% Main Estrogens CAS 50-27-1 Estriol in Treating Multiple Sclerosis

Basic Info.

Trademark

oroni

Transport Package

Aluminum Bag; Drums or as Your Request

Specification

25kg/drum

Origin

China

HS Code

2915900090

Trademark

oroni

Transport Package

Aluminum Bag; Drums or as Your Request

Specification

25kg/drum

Origin

China

HS Code

2915900090

Product Desciption

Product Description
Estriol
CAS No.: 50-27-1
Molecular Weight: 288.3814
Molecular Formula: C18H24O3
Appearance: White crystalline powder
Specification:USP
MOQ: 10g
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation.
Description of Estriol :

1. Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.

2. Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.Though initial research in the 1970s suggested it could be used therapeutically as an estrogen,subsequent research failed to confirm this hypothesis.In pregnant women with multiple sclerosis, estriol reduces the disease's symptoms noticeably, according to researchers at UCLA's Geffen Medical School.

3. Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.

4. Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not
approved for use by the FDA or Health Canada.

COA :

ITEM	SPECIFICATION	RESULT
Character	White or almost white crystalline powder	White crystalline powder
Specific rotation	+54°to +62°	+59.9°
Completeness of solution	Clear and free from undissolved solid	Conforms
Identification	(1) complies by IR (2) complies by UV	Conforms Conforms
Residue on Ignition	Not more than 0.1%	0.05%
Loss on drying	Not more than 0.5	0.1%
Chromatographic purity	Total impurities not more than 2.0%	<2.0%
Assay	It should contain 97.0% to 102.0% of C18H24O3 calculated on dried basis	98.4%
Particle size	It should be 90% below 30μm	Conforms
Conclusion	Conforms to USP36

Top Purity >99% Main Estrogens CAS 50-27-1 Estriol in Treating Multiple Sclerosis

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