High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8

China High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8, Find details about China Atorvastatin Calcium Powder, Lipitor from High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8

Model NO.
134523-03-8
Product Names
Atorvastatin Calcium
Mf
C66h68caf2n4o10
Einecs No.
200-659-6
CAS
134523-03-8
Appearance
White Powder
Storage
Dry Place
Sample
Availiable
Package
Aluminum Foil Bag or Drum
Trademark
Wucine
Transport Package
1kg/Foil Bag 25kg/Drum
Origin
Shaan Xi, China
HS Code
29372390
Model NO.
134523-03-8
Product Names
Atorvastatin Calcium
Mf
C66h68caf2n4o10
Einecs No.
200-659-6
CAS
134523-03-8
Appearance
White Powder
Storage
Dry Place
Sample
Availiable
Package
Aluminum Foil Bag or Drum
Trademark
Wucine
Transport Package
1kg/Foil Bag 25kg/Drum
Origin
Shaan Xi, China
HS Code
29372390
Product name: Atorvastatin Calcium
Appearance:White Powder
CAS:
 134523-03-8
MF: C66H68CaF2N4O10
EINECS No:200-659-6
Molecular weithgs:1155.36
Melting point:176-178°C
Purity:99%
Shelf life:2 years
Storage:Keep in cool dry place.
.
 
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8Specification:
Physical&Chemical Control
ITEMSPECIFICATIONRESULTS
AppearanceFine powderComplies
ColorlWhite yellowComplies
Odor&TasteCharacteristicComplies
Assay  ≥99%99.53%
Heavy Metals        10ppmComplies

Pb

≤2ppm

Complies

As

≤2ppm

Complies

Hg

≤1ppm

Complies

Cadmium

≤1ppm

Complies

Sulphates

300ppm

Complies
Ammonium≤200ppmComplies
Iron10ppmComplies

Microbiological Control

Total plate count

1000CFU/G

Complies

Yeast & mold

100 CFU /G

Complies

Total coli forms

100 CFU /G

Complies

E.coli   

Negative

Negative
SalmonellaNegativeNegative

 

Product description:

Lipitor was launched in Canada, the Netherlands, the UK and the US as an orally-active hypocholesterolemic agent. It was the first pharmaceutical product ever to attain over one billion dollars in sales in its first year. It can be synthesized by a number of routes but the most efficient involves the Paal-Knorr reaction of an acetonide protected dihydroxy amino ester and a diaryl phenylacetamide diketone. Lipitor is a liver selective, reversible competitive inhibitor of HMG-CoA reductase, the rate limiting step in cholesterol biosynthesis. Lipitor monotherapy resulted in a reduction of LDL cholesterol by up to 60%. Lipitor is about 2-4 times more potent, on a dosage basis, than Simvastatin. The superior properties of Lipitor can be attributed to its greater uptake and longer duration of action in the liver. In addition to its effects on cholesterol, Lipitor is also effective in lowering triglycerides. While the mechanism is not clear, two theories proposed are: a) the decrease in cholesterol causes a concomitant increase in hepatic LDL-receptor activity (mostly B and E type) which results in a decrease in triglycerides through an increase in binding of triglycerides to VLDL and LDL, and b) the decreased level of cholesterol impairs VLDL transport of triglycerides.


Function & Application:

A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.

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Certifications

 

High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8

Packaging & Shipping

High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8

Company Profile
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8

 High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
High Purity Atorvastatin Calcium for Lipid-Lowering CAS 134523-03-8
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

FAQ
1.Are you a manufacturer or trade company?
We are a professional manufacturer.
2.What's your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount.
3.What's your shipping time?
We have a large stock, which means we can deliver the goods to you immediately.
4.How do you ensure the quality of your products?
Strict QC with 6 steps testing from raw material purchase to finished product.
5.How do you ship the order normally?
For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.
6.What's your loading port?
Usually Shanghai, Qingdao, Tianjin, Guangzhou.