China Anti-Hairloss Setipiprant Sodium Powder Setipiprant CAS 866460-33-5 Ru58841, Find details about China Setipiprant, 866460-33-5 from Anti-Hairloss Setipiprant Sodium Powder Setipiprant CAS 866460-33-5 Ru58841
Product name: | Setipiprant |
CAS: | 866460-33-5 |
Appearance: | White Powder |
Purity: | 99% |
Description:
Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.
However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.
A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.
Application:
1. Increase cellular proliferation of outer root sheeth cells.
2. Increase hair diameter and hair density.
3. Increase the percentage of hair in the anagen phase.
4. Exert no negative effect on body hormone levels.
5. Provide equivalent or better net growth than Finasteride.
Packing:
1. Weight <1kg ---- Fluorinated bottle
2. 25kg ---- Plastic bucket
3. 180- 200kg ---- Drum
P.S.: we accept packaging customization.
Delivery:
We have large quantity procaine raw powder in stock, normally could ship out within 3 working days.
For rush delivery, please contact our sales team for particular arrangement.
Shipping:
We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
We keep tracking the shippment until clients well received.
After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
Qingdao Little Fox Bio-Tech Co. Ltd is a scientific and technological company integrating product research and development, manufacture and trading of chemical intermediates, specialized on organic intermediates, API ,pharmaceutical intermediates, chemical solvents and Daily chemical.
We provide DOOR-TO-DOOR shipping, including customs clearance.
1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line)
2: Various payment terms accepted (Btc; MoneyGram; WU)
3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging)
4: Efficient delivery (3-10 DAYS fast delivery service )
5: Best quality (Without any doping, all the products are pure)
6: Good reputation (we have been in this industry for years, earned great trust from our clients from allover the world)
7: Huge Capacity (We have plenty manufacture centers, each day can produce tons of various products.)
8: The most competitive price (manufacture and produce by our own factories)
9. In the end, we have the most professional experienced and dedicated team here.
Q1: Are you a manufacturer?
A:Yes, we are factory founded on 2002.
2) We can provide reasonable price, high quality product and prompt shipmen;
3) We can send the goods to your delivery addreee directly, it is relatively safe and fast;
4) Warm sfter sale service, we will help to solve the problems in your usage.