Natural CAS: 480-40-0 5, 7-Dihydroxyflavone Chrysin
China Natural CAS: 480-40-0 5, 7-Dihydroxyflavone Chrysin, Find details about China Chrysin, Purity Chrysin from Natural CAS: 480-40-0 5, 7-Dihydroxyflavone Chrysin
Basic Info.
Model NO.
480-40-0
Product Name
Chrysin
CAS Number
480-40-0
Inci
Chrysin
Molecular Weight
254.24G/Mol
Molecular Formula
C15h10o4
Appearance
Light Yellow Fine Powder
Particle Size
98% Through 80 Mesh
Application
Food Supplement
Shelf Life
2 Years
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
99%
Origin
China
Model NO.
480-40-0
Product Name
Chrysin
CAS Number
480-40-0
Inci
Chrysin
Molecular Weight
254.24G/Mol
Molecular Formula
C15h10o4
Appearance
Light Yellow Fine Powder
Particle Size
98% Through 80 Mesh
Application
Food Supplement
Shelf Life
2 Years
Trademark
Mainherb
Transport Package
1kg, 25kg
Specification
99%
Origin
China
Product Desciption
1. Chrysin Overview
Chrysin, also known as 5,7-dihydroxyflavone, is a natural flavonoid compound with extensive biological activity. Chrysin is light yellow fine powder. It is a cosmetic grade raw material obtained by synthetic method; and its purity is up to 99%. Chrysin is insoluble in water; it is soluble in lye, and appears yellow-brown; it is slightly soluble in cold ethanol, ether.
As a flavonoid compound
1.Chrysin has antiviral activity.
2.It has strong oxidation resistance and capture ability to various oxygen-containing free radicals;
3.Its inhibition activity to tyrosinase shows whitening effect. Chrysin can be used in whitening cosmetics.
4.It can absorb ultraviolet rays in region A and region B; it is an effective light protection agent. So Chrysin can be used in sun protection cosmetics;
5.It can promote generation of ceramide and collagen. It regulates skin, and resists wrinkle, also relieves skin tension. In addition,
6.Chrysin can also help to eliminate bilirubin and iron deposited under skin. It is used to fight against dark eye circles. It is very popular in eye skin care products such as eye cream and essence. Therefore, Chrysin can be used as whitening agent, antioxidant and skin toner in all kinds of effective cosmetics.
3. Specifications
4. Chrysin Manufacturer Flow Chart
Note: OOS means Out Of Specification.
5. Chrysin Benefits
1.Whitening and anti-oxidation
Chrysin inhibits COX-2 expression, and forms PGE-2. It also scavenges free radicals in human body. Thereby, it suggests that Chrysin possesses antioxidant property. Chrysin can also inhibit the activity of tyrosinase. It shows certain whitening effect. Thus Chrysin can be used in whitening cosmetics.
2.Removing dark circles
Chrysin activates UGT1A1. It helps eliminate bilirubin and iron deposits under skin (also known as dark circles). As a result, Chrysin is popular in eye creams. It is used to combat puffy eyes and dark circles around eyes.
3.Anti-inflammation
Activation of cell junction is a sign of skin disorders such as blisters, keratosis, and aceratosis. Chrysin can inhibit activation of cell junction. It has some anti-inflammatory and anti-viral effect; and it is a good anti-inflammatory agent for skin.
7. Chrysin Reference Formula
Liposomal gel
Chrysin, also known as 5,7-dihydroxyflavone, is a natural flavonoid compound with extensive biological activity. Chrysin is light yellow fine powder. It is a cosmetic grade raw material obtained by synthetic method; and its purity is up to 99%. Chrysin is insoluble in water; it is soluble in lye, and appears yellow-brown; it is slightly soluble in cold ethanol, ether.
As a flavonoid compound1.Chrysin has antiviral activity.
2.It has strong oxidation resistance and capture ability to various oxygen-containing free radicals;
3.Its inhibition activity to tyrosinase shows whitening effect. Chrysin can be used in whitening cosmetics.
4.It can absorb ultraviolet rays in region A and region B; it is an effective light protection agent. So Chrysin can be used in sun protection cosmetics;
5.It can promote generation of ceramide and collagen. It regulates skin, and resists wrinkle, also relieves skin tension. In addition,
6.Chrysin can also help to eliminate bilirubin and iron deposited under skin. It is used to fight against dark eye circles. It is very popular in eye skin care products such as eye cream and essence. Therefore, Chrysin can be used as whitening agent, antioxidant and skin toner in all kinds of effective cosmetics.
| Product Name | CAS Number | INCI | |
| Chrysin | 480-40-0 | CHRYSIN | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 254.24g/mol | C15H10O4 |  | |
2. Chrysin Source
Chrysin naturally exists in traditional materials of medicine and food homology such as scutellaria, propolis, etc. Also it is distributed in seeds of Oroxylum indicum in Bignoniaceae family and pinus monticola. However, due to the need to adapt to industrial large-scale production, Chrysin is often produced by synthesis method. Chrysin by synthetic method is 99% purity. It has a good price advantage.
3. Specifications| Product Name | Specification |
| Chrysin | 99% |
| Items | Specification |
| Assay | 99% |
| Color | Light yellow fine powder |
| Identification | IR spectrum |
| Physical Characteristics | |
| Particle Size | 98% through 80 mesh |
| Moisture | ≤0.5% |
| Ash Content | ≤0.2% |
| Heavy Metals | |
| Heavy metals | ≤10ppm |
| Microbiological Tests | |
| Total Plate count | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Escherichia coli | Negative |
| Staphylococcus | Negative |
| Salmonella | Negative |
Note: OOS means Out Of Specification.5. Chrysin Benefits
1.Whitening and anti-oxidation
Chrysin inhibits COX-2 expression, and forms PGE-2. It also scavenges free radicals in human body. Thereby, it suggests that Chrysin possesses antioxidant property. Chrysin can also inhibit the activity of tyrosinase. It shows certain whitening effect. Thus Chrysin can be used in whitening cosmetics.
2.Removing dark circles
Chrysin activates UGT1A1. It helps eliminate bilirubin and iron deposits under skin (also known as dark circles). As a result, Chrysin is popular in eye creams. It is used to combat puffy eyes and dark circles around eyes.
3.Anti-inflammation
Activation of cell junction is a sign of skin disorders such as blisters, keratosis, and aceratosis. Chrysin can inhibit activation of cell junction. It has some anti-inflammatory and anti-viral effect; and it is a good anti-inflammatory agent for skin.
6. Study on the Pharmacology of Chrysin and Cosmetics
| Test item | Concentration | Result |
| Elimination to DPPH free radicals | 100×10-6 | Elimination rate :90.51%±1.03% |
| Inhibition to lipid peroxidation | 50μg/mL | Inhibition rate:64.4% |
| Promotion to the production of ceramide by cell culture | 2μmol/L | Promotion rate:124( blank 100) |
| Promotion to the production of procollagen by cell culture | 1.5% | Promotion rate:116% ( blank 100) |
| Inhibition to tyrosinase activity | 14.8μmol/L | Inhibition rate:89.1% |
| Inhibition to toe swelling in mice | 2.5% | Inhibition rate:34.2% |
| Inhibition to PGE2 formation induced by LPS | 20μmol/L | Inhibition rate:97.2% |
| Inhibition to IL-4 formation | IC50:>30μmol/L | |
| Inhibition to TNF-α formation | 10μmol/L | Inhibition rate:15.6% |
| Inhibition to cell junction | 0.001% | Inhibition rate:75% |
| Inhibition to phototoxicity in 5J/cm2 UVA irradiation | IC50:0.05% |
Liposomal gel
| Ingredient | Content(%) | Ingredient | Content(%) |
| Chrysin | 0.1 | Lecithin | 6.0 |
| Urea | 0.2 | Shea butter | 3.0 |
| DCA | 0.5 | Ferulic acid | 0.5 |
| Hydrolyzed collagen | 2.0 | Xanthan gum | 1.4 |
| Vitamin A palmitate | 0.2 | Sorbitol | 3.0 |
| Vitamin H | 0.08 | Preservative | Appropriate |
| Sodium citrate | 0.5 | Glycerin | 0.2 |
| Purified water | Add to 100 | ||
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