Basic information

Our company

Usage And Synthesis

Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.Non Caine local anesthetic.A sodium channel blocker and DNA methylation inhibitorProcaine hydrochloride is a local anesthetic agent.Small, colorless crystals or white, crys- talline powder; odorless; stable in air. Soluble in water and in alcohol at 25C; slightly soluble ; almost insoluble in ether; solutions acid to litmus.Procaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia. 
White fine needle crystal or crystalline powder at room temperature, no smell, taste slightly bitter and Ma, soluble in water, soluble in ethanol, slightly soluble, almost insoluble in ether. Procaine hydrochloride ester bond structure can be hydrolyzed to produce amino acid and diethylaminoethanol, under certain conditions, the amino acid may be further decarboxylated toxic.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ºC steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save. 
The product structure of aromatic primary amino group in dilute can generate diazonium, coupling salt, reaction occurs when add alkaline β-naphthol, generating azo compounds scarlet.
The above information is edited by the chemicalbook of Kui Xiongfeng.
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects. 
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically  It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

Our service

 1.Cooperate with research institutions, we strictly control the process from raw material to finished product.

 2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.

 3.We can send the goods to your delivery address directly. It is relatively safe and fast. 

 4.Quick and clear response to customers questions.

 5.We could make our price discount if you place a substantial order with us.

 6.Products can be packaged according to customer requirements.


FAQ

Q1. Have your Product Quality been Approved by the Third Party Lab?
A: Yes, all the products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 

Q2. Is there any discount?
A: Of course, for the larger quantity, we always support with better price for our further cooperation. 

Q3. What is your package?
A: Powder: PE bag, glass bottle or PTFE bottle for inner packing, and then into the aluminium foil bag for outer packing.
Liquid: glass bottle or PTFE bottle for inner packing, and then into the aluminium foil bag for outer packing.
Bulk order: Fiber drum or steel drum.

Q4. Will you provide the sample for testing the quality?
A: We'd like to offer free samples to our clients for the quality evaluation for most products, but the shipping cost is borne by clients.

Q5. What are the payment terms?
A: We can accept the T/T, Western Union, Money Gram, PayPal, Bitcoin etc.

Q6. How long does it take the goods to arrive?
A: It is depending on your location,
For the small order, please expect the 5-7 days by DHL, UPS, TNT, FEDEX, EMS and so on.
For the mass order, please allow the 5-8 days by Air or 20-35 days by Sea.

Q7. How do you treat quality complaint?
A: First of all, our QC department will do the strict examination of our export products by HPLC, UV, GC, TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem, caused by us, we will send you free goods for replacement or refund your loss.

Packaging And Shipment