Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir
China Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir, Find details about China Dolutegravir, Dolutegravir Powder from Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir
Basic Info.
Model NO.
D-sung Dolutegravir
Product Name
Dolutegravir
Name
Dolutegravir Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical; Anti-Viral
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
1051375-16-6
Mf
C20h19f2n3o5
MW
419.38
Boiling Point
668.958 °c at 760 Mmhg
Density
1.53
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Dolutegravir
Product Name
Dolutegravir
Name
Dolutegravir Powder
Appearance
White Powder
Color
White
Grade
Pharmaceutical Grade
Assay
HPLC 99%
Application
Pharmaceutical; Anti-Viral
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
1051375-16-6
Mf
C20h19f2n3o5
MW
419.38
Boiling Point
668.958 °c at 760 Mmhg
Density
1.53
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Raw Material CAS 1051375-16-6 Dolutegravir 99% Purity Dolutegravir Pharmaceutical Intermediate Dolutegravir
| Product name | Dolutegravir |
| Appearance | White powder |
| CAS NO. | 1051375-16-6 |
| MF | C20H19F2N3O5 |
| MW | 419.38 |
Dolutegravir (Dolutegravir, Tivicay) is a new anti-AIDS drug developed by the British pharmaceutical giant GlaxoSmithKline (GSK) and Japan's Shionogi Pharmaceutical Company (Shionogi). In July 2012, GlaxoSmithKline Pharmaceuticals and Shionoyoshi Pharmaceuticals announced the results of the Phase III clinical trial of the new AIDS drug Dolutegravir. After receiving dolutegravir and two other old-version AIDS drugs for 48 weeks, 88% of the patients' bodies The virus was successfully suppressed, and Gilead Sciences' three-in-one oral drug Atripla (Efavirenz/Emtricitabine/TenofovirDisoproxilFumarate) After that, 81% of the virus in the patient's body was suppressed. It can be seen that the dolutegravir drug of GlaxoSmithKline is slightly better. According to the researchers, in the comparison trial, due to the side effects of the drug, 10% of the patients eventually stopped taking Gilead's Atripla drug, but only 2% of the patients stopped taking GlaxoSmithKline's dolutegravir. Drugs, it can be seen that the safety of GlaxoSmithKline dolutegravir is slightly higher.
Dulutvir sodium salt is a second-generation HIV-1 integrase chain transfer inhibitor. Dulutvir sodium is currently in phase III clinical trials for the treatment of HIV infection. It has been shown that Dulutvir Chemicalbook sodium salt can effectively inhibit HIV replication in cells infected with inactivated PHIV lentiviral vectors (such as peripheral blood mononuclear cells (PBMC), MT-4 cells and CIP4 cells).
Dulutvir sodium salt is a second-generation HIV-1 integrase chain transfer inhibitor. Dulutvir sodium is currently in phase III clinical trials for the treatment of HIV infection. It has been shown that Dulutvir Chemicalbook sodium salt can effectively inhibit HIV replication in cells infected with inactivated PHIV lentiviral vectors (such as peripheral blood mononuclear cells (PBMC), MT-4 cells and CIP4 cells).
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