Top Quality 99.9% Raw Powder Isotretinoin Powder CAS- 4759 -48-2 with Best Price

China Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price, Find details about China 4759-48-2, CAS 4759-48-2 from Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price

Basic Info.

Model NO.

4759-48-2

Storage Condition

Store at Rt

Trademark

FOUSI

Transport Package

Aluminium Foil Bag

Specification

Origin

China

HS Code

2936210000

Model NO.

4759-48-2

Storage Condition

Store at Rt

Trademark

FOUSI

Transport Package

Aluminium Foil Bag

Specification

Origin

China

HS Code

2936210000

Product Desciption

Top Quality 99.9% Raw Powder Isotretinoin Powder
CAS-4759-48-2 with Best Price

{Product Name}:	Isotretinoin
{Other Name}:	TretinoinImpurity1(TretinoinEPImpurityA);AntiAcnePowerfulIsotretinoinPowderIsotretinoinPharmaceuticalRawMaterials;IsotretinoinCapsules;Isotretinoin-D5/13-cChemicalbookis-Retinoicacid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoicacid;ISOTRETINON;AdifferentdiMensionacid
{Appearance}:	Yellow Powder
{Specification}:	99%
{MOQ}:	1kg

Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price

Melting point	172-175 °C (lit.)
Boiling point	381.66°C (rough estimate)
density	1.0597 (rough estimate)
refractive index	1.4800 (estimate)
storage temp.	-20°C
solubility	Practically insoluble in water, soluble in meth ylene chlo ride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka	4.76±0.33(Predicted)
form	Fine Crystalline Powder
color	Yellow-orange to orange
Water Solubility	insoluble
λmax	354nm(EtOH)(lit.)
Merck	14,5228

Appliction

Isotretinoin is an effective drug against acne. It takes effect on four processes of acne procedures, preventing the formation of acne lesions: inhibiting sebaceous secretion; inhibit the growth of acne bacillus; inhibiting sebaceous hyperplasia; anti-inflammatory effect. Isotretinoin has no affinity to Vitamin A acid receptors. Its exact mechanism of action is not very clear. Its anti-acne role may be related to that it or its metabolites can inhibit the proliferation and differentiation of sebaceous glands. It may also reduce the volume of the sebaceous glands, reducing the skin's DHT, down-regulate the expression of skin androgen receptor. Other possible mechanism includes reducing the hair follicle keratosis, antibacterial, anti-inflammatory effects and so on. In the 1980s, Isotretinoin is only for treating severe nodular cystic acne. Isotretinoin is now also used for treating some less-seriously acne where those related patients are often insensitive to conventional therapy, especially some patients with long-term use of antibiotics due to that acne bacillus have evolved multiple drug (such as erythromycin, tetracycline) resistance. It may also be used for some acne patients prone to scar.

Top Quality 99.9% Raw Powder Isotretinoin Powder CAS-4759-48-2 with Best Price