CAS:7689-03-4
Product name:Camptothecin
English alias:Camptothecin; Baicalin std.; CAMPTOTHECINE; d-Camptothecin; CaMpathecin;
Molecular formula::C20H16N2O4
Molecular mass::348.35200
EINECS:444-280-6
Appearance and character:Yellowish crystal powder
Density:1.51 g/cm3
Melting point:260 °C (dec.)(lit.)
Boiling point:264ºC
Flash point:411.6ºC
Refractive index:1.787
Water solubility:insoluble
Storage conditions:The warehouse is low-temperature, ventilated and dry, and stored separately from food raw materials
, m ethanol   and ethanol. The solution shows violet blue fluorescence under ultraviolet lamp,
It is easy to deteriorate when exposed to light, slightly hygroscopic, yellow green when exposed to concentrated sulfuric acid, yellow green fluorescence when diluted with distilled water, and alkaline.

Camptothecin (CPT) is a cytotoxic q uinoline alkaloid,
It can inhibit DNA topoisomerase (topo I). In 1966, M.E. wall and M.C. Wani systematically screened natural substances,
And then found the new anticancer drugs.
Camptothecin was isolated from the bark and branches of Camptotheca acuminata (Camptotheca acuminata, Camptotheca acuminata) in China, and it was a traditional Chinese medicine treatment for cancer in the early stage.
Camptothecin has significant anticancer properties, low solubility and high adverse drug reactions in preliminary clinical trials.
Pharmaceutical chemists have developed a variety of synthetic camptothecin and various derivatives to increase the good effect.
Currently, two camptothecin analogues have been approved for cancer chemotherapy, such as topotecan and irinotecan.