Products

GMP High Quingity Atropine Sulfate Injection

China GMP High Quingity Atropine Sulfate Injection, Find details about China Anti-Shock, Rescue Organophosphate Poisoning from GMP High Quingity Atropine Sulfate Injection

Model NO.
Pain killer detoxification
HS Code
2939800000
Model NO.
Pain killer detoxification
HS Code
2939800000
Product nameAtropine sulfate injection
Main Ingredientsatropine sulphate
Adaptation disease1. All kinds of visceral colic, such as gastrointestinal colic and bladder irritation symptoms.  The effect on biliary colic and renal colic is poor.  2. Severe night sweats and salivation before general anesthesia; 3. Slow arrhythmias such as sinoatrial block and atrioventricular block caused by over-excitation of vagus nerve can also be used for ventricular ectopic node secondary to low function of sinoatrial node; 4. Anti-shock;  5. Rescue organophosphate poisoning.  
Dosage formLiquid dosage form
CharacterThis product is a clear colorless liquid
Specification(1)2 mL:1mg    (2) 1 ml:5mg   (3)1 ml:10mg    (4)1 mL:0.5mg
Usage and dosage1. Normal dosage for subcutaneous, muscular or intravenous injection for adults: 0.3 ~ 0.5 mg each time, 0.5 ~ 3 mg a day;  Maximum dose: 2 mg at a time.  Subcutaneous injection for children: 0.01 ~ 0.02 mg/kg each time, 2-3 times a day.  Intravenous injection: for the treatment of A-S syndrome, 0.03-0.05 mg/kg each time, 15 minutes if necessary, repeat once, until flushing, circulation improvement, blood pressure rise, extend the interval to blood pressure stability. 
2. Anti-arrhythmia adult intravenous injection 0.5 ~ 1 mg, 1 ~ 2 hours as required, the maximum amount is 2 mg. 
3. Detoxification (1) for antimony agent caused by a-SI syndrome, intravenous injection of 1 ~ 2 mg, 15 ~ 30 minutes after the injection of 1 mg, if the patient has no attack, as required every 3 ~ 4 hours subcutaneous or intramuscular injection of 1 mg.  (2) for organophosphorus poisoning, muscle injection or intravenous injection 1 ~ 2 mg(serious organophosphorus poisoning can increase 5 ~ 10 times), every 10 ~ 20 minutes repeat, until the blue and purple disappear, continue to use drugs to stabilize the condition, and then maintain the amount, sometimes need 2 ~ 3 days. 
4. For adults with anti-shock improvement cycle, 0.02-0.05 mg/kg body weight should be diluted with 50% glucose injection and then injected intravenously or diluted with glucose water and then dropped intravenously. 
5. Before anesthesia for adults 0.5 ~ 1 hour before surgery, intramuscular injection 0.5 mg, subcutaneous injection dosage for children:  For those weighing less than 3 kg, 0.1 mg, 0.2 mg for 7-9 kg, 0.3 mg for 12-16 kg, 0.4 mg for 20-27 kg, and 0.5 mg for those weighing more than 32 kg.  
StorageAirtight save
OriginChina
validity24 months
TatooGlaucoma and prostatic hypertrophy, high fever forbidden.
Notice[Precautions] 
1. Intolerant to other belladonna alkaloids, intolerant to this product. 
Intravenous atropine in pregnant women can cause fetal tachycardia. 
3. This product can secrete into milk and inhibit lactation. 
4. Infants and young children are very sensitive to the toxic reaction of this product, especially children with spasmodic paralysis and brain damage. The reaction is stronger. 
5. The elderly are prone to anti-m cholinergic side effects, such as dysuria, constipation and dry mouth (especially in men), which are also prone to induce undiagnosed glaucoma. Once found, the drug should be stopped immediately.  This product is especially easy for the elderly to reduce sweat secretion, affecting heat dissipation, so use with caution in summer. 
6. The following conditions should be used with caution :(1) brain damage, especially in children;  (2) heart disease, especially arrhythmia, congestive heart failure, coronary heart disease, mitral stenosis, etc.;  (3) Reflux esophagitis, reduced movement of the esophagus and stomach, relaxation of the lower esophageal extender muscle, can delay gastric empties, thereby promoting gastric retention, and increase gastroesophageal reflux;  (4) It is forbidden for glaucoma patients. Latent glaucoma may be induced in patients over 20 years old.  (5) Ulcerative colitis, reduced intestinal motility when the dosage is large, can lead to paralytic intestinal obstruction, and can induce aggravating toxic megacolon disease;  (6) Urinary tract infection (reduced bladder tone) and urinary tract obstruction caused by prostatic hypertrophy may lead to complete urinary retention. 
7. Interference to diagnosis: phenolphthalein test can reduce the emission of phenolphthalein. 
[Medication for pregnant and lactating Women] The safety of this product for pregnant women is not clear, and the advantages and disadvantages of this product should be considered for pregnant women.  This product can be secreted to milk, and has the effect of inhibiting lactation, lactation women should use with caution. 
[Drug for children] Children's brain is sensitive to this product, especially when they have fever, it is easy to cause central disorders, so use with caution. 
Medication for the elderly Elderly patients, especially those over 60 years old, are susceptible to glandular secretion, so use this product with caution. 
[Drug interaction] 
(1) Atropine excretion is delayed, action time and/or toxicity are increased when it is used with uretalinizing agents including acid-making agents containing magnesium or calcium, carbonic anhydrase inhibitors, sodium bicarbonate and citrate, etc. 
(2) The adverse reactions of atropine may be intensified when it is used with amantadine, phenothiazine, other anticholinesteric drugs, pimedone, procainamide and tricyclic antidepressants. 
(3) When combined with monoamine oxidase inhibitors (including furazolidone, procarbazid, etc.), the side-effects of anti-m choline action can be strengthened. 
(4) When combined with metoclopramide, the gastrointestinal motility of metoclopramide could be antagonized. 
[Drug overdose] The maximum intravenous dose of 2 mg each time, exceeding the above dosage, will cause poisoning.  The minimum lethal dose for adults is about 80 to 130 mg.  Overdoses are characterized by clumsy and unsteady movements, confusion, convulsions, difficulty breathing, and abnormally rapid heartbeat. 
Pharmacology toxicology This product is a typical M choline receptor blocker.  In addition to the general anti-m choline effect to relieve gastrointestinal smooth muscle spasm, inhibit glandular secretion, dilate pupils, increase intraocular pressure, vision regulation paralysis, heart rate acceleration, bronchiectasis, etc., high dose can act on vascular smooth muscle, dilate blood vessels, relieve spasmodic contraction, improve microcirculation.  In addition, this product can stimulate or inhibit the central nervous system, with a certain dose - dependent.  The effect on the smooth muscle of heart, intestine and bronchus is stronger and longer lasting than other belladonna alkaloids. 
[Pharmacokinetics] Peak blood concentration 15 ~ 20 minutes after intramuscular injection, 1 ~ 2 hours after oral administration, generally lasting 4 ~ 6 hours, longer dilation of pupil aging.  T1/2 is 3.7-4.3 hours.  Mainly through hydrolytic metabolism of hepatocyte enzymes, about 13% ~ 50% are excreted in the urine in their original form within 12 hours.  
[Adverse reactions] 
The adverse reactions caused by different doses were as follows: 0.5 mg, slight slow heart rate, slight dry mouth and little sweating;  1 mg, dry mouth, accelerated heart rate, slightly dilated pupils;  2 mg, palpitations, significant dry mouth, dilated pupils, sometimes blurred vision;  5 mg, the above symptoms are aggravated, accompanied by slurred speech, irritability, dry skin and fever, difficulty urinating, reduced bowel motility;  Above 10 mg, the above symptoms are more serious, rapid and weak pulse, serious central excitation, accelerated and deepened breathing, delirium, hallucinations, convulsions, etc.  Severe poisoning can be inhibited by central excitement, coma and respiratory paralysis.  The lowest lethal dose is about 80-130 mg for adults and 10 mg for children.  Fever, rapid pulse, diarrhea and the elderly with caution.  
GMP High Quingity Atropine Sulfate InjectionGMP High Quingity Atropine Sulfate Injection
This product is a water injection, the composition is atropine sulfate, please keep airtight.  

This product is mainly used for anti-shock, rescue organophosphate poisoning, the treatment of various visceral colic, the treatment of slow arrhythmia, general anesthesia before the administration of drugs, the treatment of severe night sweats, salivation and other symptoms.  

This product is colorless and clear liquid, we use glass ampoules, glass bottles can choose colorless and brown, 10 pieces per box, there are many content specifications for you to choose:
(1)2 mL:1mg (2) 1 mL: 5mg (3)1 mL: 10mg (4)1 mL:0.5mg.  

Usage and precautions please refer to the above table or follow the doctor's advice.  

To get more information, just feel free to contact with us.  Thanks. 
Sunny 112832913@qq.com

You Might Also Like