China Supply Fenofibrate 49562-28-9//Pitavastatin 147511-69-1//134523-03-8 Atorvastatin Calcium//134523-00-5 Atorvastatin//75330-75-5 Lovastatin/Monacolin K, Find details about China Lovastatin, Monacolin K from Supply Fenofibrate 49562-28-9//Pitavastatin 147511-69-1//134523-03-8 Atorvastatin Calcium//134523-00-5 Atorvastatin//75330-75-5 Lovastatin/Monacolin K
Introduction
Product Name | Lovastatin |
Alias | Lovastatin |
CAS | 75330-75-5 |
MF | C24H36O5 |
MW | 404.54 |
Purity | 99% |
Appearance | White powder |
Certification | ISO 9001, USP, BP |
Standard | Enterprise Standard |
Function
Lovastatin (Merck's Mevacor) is a member of the drug class of statins, used in combination with diet, weight-loss, and exercise for lowering cholesterol (hypolipidemic agent) in those with hypercholesterolemia to reduce risk of cardiovascular disease. Lovastatin is a naturally occurring drug found in food such as oyster mushrooms and red yeast rice.
Application
1. It is as a novel lipid regulating drugs-The inhibitor of HMG-CoA (β-hydroxy, β-methyl-glutaryl coenzyme A) reductase. It can significantly reduced serum total cholesterol level. After oral administration, it is hydrolyzed into corresponding β-hydroxy acid by 3-hydroxy-3-methylglutaryl coenzyme A reductase, and thus inhibiting the cholesterol biosynthesis. It is clinically used for treating heterozygous familial hypercholesterolemia, severe or mild hypercholesterolemia and light. It can also as an ancillary drug of dietary treatment for reducing the levels of excessively cholesterol and low-density protein cholesterol.
2. It is a cardiovascular systematic drug which can prevent the development of atherosclerosis and reduce the risk of myocardial infarction.
3.It is used for treating heterozygous familial and non familial, secondary hyperlipidemia, namely diabetes and nephrotic syndrome secondary hypercholesterolemia. It can reduce the level of TC, LF, LDL-C, and increase the level of HDL-C, reduce the risk of myocardial infarction, unstable angina and the necessity for percutaneous transluminal coronary angioplasty (PTCA).
Specification
Product Name | Lovastatin |
Alias | Mevinolin, 6-alpha-Methylcompactin;Mevinolin, Monacolin K, L 154803, MB 530B, MSD 803;Lovastatin (Mevacor); |
CAS No | 75330-75-5 |
MF | C24H36O5 |
MW | 404.54 |
EINECS | 1308068-626-2 |
Purity | 99% |
Appearance | White powder |
Melting Point | 175°C |
Standard | Enterprise Standard |
Usage | An antihypercholesterolemic agent. |