China High Purity Medical Intermediate Mifepristone / Mifepristoe CAS 84371-65-3, Find details about China 84371-65-3, Hormone Powder Mifepristone from High Purity Medical Intermediate Mifepristone / Mifepristoe CAS 84371-65-3
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient. The original target for the research group, however, was the discovery and development of compounds with antiglucocorticoid properties. These antiglucocorticoid properties are of great interest in the treatment of severe mood disorders and psychosis, although a review of published articles was inconclusive on their efficacy, and considered the use of these drugs in mood disorders at 'proof of concept' stage. It is on the World Health Organization's List of Essential Medicines.
Function
new anti-progesterone, and has anti-glucocorticoid activity, but not progesterone, estrogen, androgen and anti-estrogen activity. and progesterone receptor affinity 5-fold stronger than progesterone. for anti-early pregnancy, reminders by only pregnancy, fetal death, uterine induction of labor, etc.
TEST ITEMS | SPECIFICATION | RESULTS |
Description | : White Crystalline Powder | White Powder |
Identification | : Positive | Positive |
Assay(by HPLC) | : 98.0~102.0% | 99.34% |
Absorbance(E1cm) | : 465~495 | 482.5 |
Melting Point | : 191~195°C | 193.5~195.0°C |
Loss On Drying | : 0.5%max | 0.19% |
Specific Rotation | : +288°~ +298° | +290.2° |
Residue On Ignition | : 0.1%max | 0.03% |
Related Substances | : Total:1.5%max | <1.3% |
Single:0.5%max | <0.4% | |
Residue Solvents | : 0.2%max | 0.10% |
Heavy Metals | : 20PPm max | <10PPm |
Conclusion | The specification conform with enterprise standard. |
Packing
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