China 99.8% High Quality Levothyroxine Sodium T4 CAS: 25416-65-3, Find details about China 25416-65-3, Sodium Levothyroxine from 99.8% High Quality Levothyroxine Sodium T4 CAS: 25416-65-3
Quick Details:
Product Name: Sodium levothyroxine
Synonyms: SODIUM LEVOTHYROXINE;SODIUM LEVOTHYROXINE, HYDRATE;sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate;3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE;L-THYROXINE SODIUM SALT;L-THYROXINE SODIUM SALT, HYDRATE;L-THYROXINE SODIUM, HYDRATE;
CAS: 25416-65-3
MF: C15H10I4NNaO4
MW: 798.85
EINECS: 200-221-4
Product Categories: Hormone Drugs
Items Specifications
Appearance: White crystals ,crystalline powder
Assay: 99.7%
Specific Rotation: -0.10 o --- +0.10 o
Residue on ignition: 0.10% max
Water-insoluble substance: 0.1% max
Fumaric Acid: 1.0% max
Maleic Acid: 0.05% max
Heavy metals(as Pb): 10 ppm max
Arsenic(As) : 4 ppm max
Description:
Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
cholesterol levels) but was withdrawn due to cardiac side effects. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Levothyroxine (INN, USAN) or L-thyroxine is a synthetic thyroid hormone that is chemically identical to thyroxine (T4), which is naturally secreted by the follicular cells of the thyroid gland. It is used to treat thyroid hormone deficiency, and occasionally to prevent the recurrence of thyroid cancer. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form. The related drug dextrothyroxine (D-thyroxine) was used in the past as a treatment for hypercholesterolemia (elevated
cholesterol levels) but was withdrawn due to cardiac side effects.
Levothyroxine is typically used to treat hypothyroidism, and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy. It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing. Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
Applications :
Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.
COA:
| Specification | Result | |
Appearance | An odorless, almost white or buff colored powder | pass | |
Solubility | 1,Very slightly soluble in water | pass | |
2,slightly soluble in alcohol | pass | ||
3,practically insoluble in most other organic solvents | pass | ||
4,disolves in diluted aqueous sodium hydroxide solutions | Pass | ||
Identification | a) Heat about 50 mg with a few drops of sulfuric acid in a porcelain crucible: violet vapors of iodine are evolved. | pass | |
b)The retention time of the major peak is confirm to the RS | pass | ||
Loss on Drying | Not more than 4.0% | 0.46% | |
|
| +20.9o | |
Assay(HPLC) | Not less than 95.0% | 99.70% | |
Levothyroxine sodium | Not more than 5.0% | 0.68% | |
Conclusion: | Up to the Standard for Export |
How to make an order :
1. Name what your need ( which product , quantity )
2. Full payment would be done once we come to an agreement on all details .
3. Parcel would be shipped out upon receipt of payment .
4. Info about parcel would be offered ( Photo , tracking number )
5. Finally you would get the parcel in 3~7 days .
Payment and Shipping:
Our service:
1.We have experience in exporting Pharmaceutical intermediates .
2.Professional packing with professional materials
3. We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
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Our Advantages:
1,High quality under strict QC/QA system with GMP factory price
2,Fast and safe delivery with secure and discreet shipment
3,Providing complete services with our resource integration, we can thus create more competitive
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