China GMP Factory Supply Good Quality Venlafaxine CAS 93413-69-5 Raw Powder High Purity 99% Venlafaxine, Find details about China Raw Powder Venlafaxine Price, High Purity 99% Venlafaxine Price from GMP Factory Supply Good Quality Venlafaxine CAS 93413-69-5 Raw Powder High Purity 99% Venlafaxine
GMP Factory Supply Good Quality Venlafaxine cas 93413-69-5 Raw powder high Purity 99% Venlafaxine
Common Name | Venlafaxine | ||
---|---|---|---|
CAS Number | 93413-69-5 | Molecular Weight | 277.402 |
Density | 1.1±0.1 g/cm3 | Boiling Point | 397.6±27.0 °C at 760 mmHg |
Molecular Formula | C17H27NO2 | Melting Point | 72-74°C |
MSDS | N/A | Flash Point | 194.2±23.7 °C |
TEM | SPECIFICATION | METHOD REFERENCE |
Appearance | white powder | Visual |
Ammonium | ≤200ppm | USPmonograph |
Chloride | ≤200ppm | USP35<221> |
Sulfate | ≤300ppm | USP35<221> |
Iron | ≤10ppm | USP35<241> |
Arsenic | ≤2ppm | USP35<211> |
Heavy metals | ≤10ppm | USP35<231>Method I |
Loss on drying(3h at 105 ºC) | ≤0.5% | USP35<731> |
Residue on Ignition | ≤0.1% | USP35<281> |
Total impurities | ≤2.0% | USP monograph |
Assay(dry basis) | 98.0% to 101.0% | USP monograph |
Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.
Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms.
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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.