China CAS: 78110-38-0 Aztreonam, Find details about China Aztreonam, Aztreonam Powder from CAS: 78110-38-0 Aztreonam
Name | Aztreonam |
Cas | 78110-38-0 |
Molecular Formula | C13H17N5O8S2 |
Appearance | White powder |
Grade | Cosmetic grade/Food Grade/Medicine Grad |
Function
Mainly used for infections caused by sensitive gram-negative bacteria, including pneumonia, pleurisy, abdominal infection, biliary tract infections, bone and joint infections, skin and soft tissue inflammation, especially for urinary tract infections, also used in sepsis. This product has a good resistance to enzyme performance when micro-organisms is not sensitive to the penicillins, cephalosporins, aminoglycosides and other drugs, the should often be effective.
Applicatioin
Anti-bacteria.Aztreonam has strong activity against susceptible gram-negative bacteria, including Pseudomonas aeruginosa. It has no useful activity against gram-positive bacteria or anaerobes. It is known to be effective against a wide range of bacteria including Citrobacter, Enterobacter, E coli, Haemophilus, Klebsiella, Proteus, and Serratia species.
Synergism between aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa has been suggested.
Aztreonam is often used in patients who are penicillin allergic or who can not tolerate aminoglycosides.
Our company can offer the raw material of Aztreonam and Aztreonam for injection.We sell our products according to customers' request.
Items | Specification | Analysis Result | |
Appearance | White, odorless crystalline powder | Conform | |
Identification | The retention times of the major peaks in the chromatogram of the assay preparation correspond to those of the Standard preparation obtained in the assay | Conform | |
Color of Solution | Not more than yellow or greenish- yellow Reference Solution II | Conform | |
Clarity of solution | Not more than Turbidity Standard I | Conform | |
PH | 4.5~7.5 | 5.2 | |
Related Impurities | Single impurities | Not more than1.0% | 0.34% |
Total impurities | Not more than3.0% | 1.25% | |
Water Content | Not more than 2.0% | 0.3% | |
Residue of ignition | Not more than 0.1% | Conform | |
Heavy Metals | Not more than 30ppm | Conform | |
Bacterial Endotoxins | Not more than 0.17EU/mg (Aztreonam) | Conform | |
Sterility Test | Sterile (without germs in 14 days) | Conform | |
Particulate matter | ≥10µm, no more than 2500/g ≥25µm, no more than 250/g | 1084 67 | |
Assay | Contain C13H17N5O8S2 90.0% ~105.0% (Calculated on anhydrous substance without L-Arginine ) | 99.5% | |
L-Arginine content | 42%~45% |