China GMP Factory Direct Supply 99% Purity USP Grade Tenofovir Powder CAS: 147127-20-6, Find details about China Tenofovir, Tenofovir Powder from China GMP Factory Direct Supply 99% Purity USP Grade Tenofovir Powder CAS: 147127-20-6
1. Antiviral drugs, Tenofovir is an acyclic nucleoside antiviral reverse transcriptase inhibitor. The active substance is Tenofovir disoproxil, while tenofovir is a prodrug that is used because of its better absorption in the gut.
2. Tenofovir can inhibit viral polymerase through direct competitively combine with natural deoxyribose or by insertion to terminate chain of human DNA. It is the first nucleotide analogs to treat HIV-1 infection that approved by the US Food and Drug Administration (FDA).
3. Tenofovir is a main medicine in AIDS cocktail therapy, researches has shown that it can effectively improve the monkeys` ability on prevention of immunodeficiency virus (similar to the human AIDS virus).
Tenofovir is a drug used to treat human immunodeficiency virus (HIV) infection. Tenofovir is an antiviral drug called a nucleotide reverse transcriptase inhibitor.
This medicine can reduce the amount of HIV in the blood and increase the number of CD4 cells (T-cells) in the blood. Additionally, tenofovir is used in combination with other drugs to treat the HIV virus.
Despite that tenofovir will not cure or prevent HIV infection or AIDS, it can help keep HIV from reproducing which may slow down the destruction of the immune system.
Items of analysis | Specification | Results |
Appearance | White powder or off-white powder | White Powder |
Identification | Must conform to reference standard | Conforms |
Water | NMT3.0% | 1.53% |
Residue on ignition | NMT2.0% | 1.07% |
Specific Rotation | -19.0°~-23.0° | -22.5° |
Sulphated ash | ≤1.5% | 0.27% |
Single impurity | ≤1.0% | 0.29% |
Total impurity | ≤3.0% | 1.11% |
Assay(Titrimetry) | 98.0%-102% | 98.60% |
9-Propenyl adenine | ≤100ppm | Conforms |
PMPA Monoester Impurity | ≤1.5% | 0.35% |
Conclusion | Qualified |
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