Amoxicillin, also known as amoxicillin or amoxicillin, is one of the most commonly used semi-synthetic penicillin broad-spectrum β-lactam antibiotics. It is a white powder with a half-life of approximately 61.3 minutes. It is stable under acidic conditions, and the gastrointestinal absorption rate reaches 90%. Amoxicillin has a strong bactericidal effect and a strong ability to penetrate cell membranes. It is one of the most widely used oral semi-synthetic penicillins. Its preparations include capsules, tablets, granules, dispersible tablets, etc., and are now often combined with clavulanic acid to make dispersible tablets.

1.Amoxicillin is a semi-synthetic broad-spectrum penicillin. Its antibacterial spectrum and antibacterial activity are basically the same as ampicillin, but its acid resistance is stronger than ampicillin, and its bactericidal effect is stronger and faster than the latter, but it cannot be used for the treatment of meningitis. . The half-life is approximately 61.3 minutes. Amoxicillin is stable under acidic conditions, with a gastrointestinal absorption rate of 90%, which is more rapid and complete than ampicillin. It has similar effects except for Shigella that is less effective than ampicillin.
2.Amoxicillin has a strong bactericidal effect and a strong ability to penetrate cell walls. After oral administration, the lactam group in the drug molecule is immediately hydrolyzed to form a peptide bond, which is quickly combined with the transpeptidase in the bacteria to inactivate it, cutting off the only way that the bacteria rely on the transpeptidase to synthesize glycopeptides to build the cell wall, making the bacteria The cells quickly become spherical bodies and rupture and dissolve. The bacteria eventually swell and die due to the loss of the cell wall and the continuous penetration of water. It has strong antibacterial and bactericidal effects on most pathogenic G+ bacteria and G- bacteria (including cocci and bacilli). Among them, Streptococcus pneumoniae, Streptococcus hemolyticus and other Streptococcus species, penicillinase-non-producing Staphylococcus, Enterococcus faecalis and other aerobic gram-positive cocci, Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae , Neisseria gonorrhoeae and other aerobic gram-negative bacteria that do not produce β-lactamase and Helicobacter pylori have good antibacterial activity. Hemodialysis can remove some drugs, but peritoneal dialysis has no effect on removing this product.