Pure Nutrition Supplement Raw Powder Palmitoylethanolamide CAS 544-31-0 Nootropics Pea Product name: Palmitoylethanolamide Powder |
Other Name: Palmitoylethanolamide(PEA),PalMitoylethanolaMide;N-(2-Hydroxyethyl)hexadecanaMide |
Appearance:White Powder |
CAS:544-31-0 |
M.F:C18H37NO2 |
M.W.:299.49 |
Specification:99% |
Palmitoylethanolamide(pea) Powder is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists.
PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α).
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ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Palmitoylethanolamide Is a natural substance identical to the body's own.
Palmitoylethanolamide In scientific literature, PEA is described as a very promising substance for various disorders that are accompanied by inflammations and infections.
Palmitoylethanolamide (N-palmitoylethanolamine) can be found in food, such as meat, eggs, soybeans and peanuts.
Palmitoylethanolamide Can be used in combination with medication, antibiotics, anti-fever and anti-coughing medication, analgesics and/or anti-inflammatory agents.
Palmitoylethanolamide There are no known problematic side-effects of PEA (Palmitoylethanolamide 544-31-0).
Palmitoylethanolamide Regularly there are two forms: Palmitoylethanolamide powder and Ultra-micronized palmitoylethanolamide powder, the micronized palmitoylethanolamide is much easier to absorb than common one. As one dietary supplement sold on the market, palmitoylethanolamide supplement is usually made into capsule and softgel form.
Application:PEA has been explored in humans; spanning various clinical trials in a variety of pain states, for inflammatory and pain syndromes. Its positive influence in atopic eczema for instance seems to originate from PPAR alpha activation. PEA is available for human use as a dietary supplement.
In a 2012 review, all clinical trials to date were summarized. In a 2015 analysis of a double blind placebo controlled study of PEA in sciatic pain, the Numbers Needed to Treat was 1.5. Its positive influence in chronic pain, and inflammatory states such as atopic eczema, seems to originate mainly from PPAR alpha activation. Since 2012 a number of new trials have been published, among which studies in glaucoma. PEA also seems to be one of the factors responsible for the decrease in pain sensitivity during and after sport, comparable to the endogenous opiates (endorphines).
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We accept Changing, Reshipping or Refunding service if any quality problem.