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Factory Supply CAS 78628- 80 -5 Terbinafine HCl Powder

China Factory Supply CAS 78628-80-5 Terbinafine HCl Powder, Find details about China Terbinafine HCl Powder, Terbinafine HCl from Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

Model NO.
HRK-Terbinafine HCl
Product Name
Terbinafine HCl Powder
Appearance
White Crystalline Powder
Test
HPLC
Mf
C21h25n
CAS
78628-80-5
MW
327.9
Active Ingredient
Terbinafine HCl
Sample
Terbinafine HCl Avaliable
Certificate
GMP ISO USP Bp
Assay
90% Min
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Application
Vertinary Raw Materials
Type of Product
Auxiliaries and Other Medicinal Chemicals
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Trademark
Henrikang
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Tetramisole HCl
Origin
Shaanxi China
Model NO.
HRK-Terbinafine HCl
Product Name
Terbinafine HCl Powder
Appearance
White Crystalline Powder
Test
HPLC
Mf
C21h25n
CAS
78628-80-5
MW
327.9
Active Ingredient
Terbinafine HCl
Sample
Terbinafine HCl Avaliable
Certificate
GMP ISO USP Bp
Assay
90% Min
Grade Standard
Feed Grade, Food Grade, Medicine Grade
Application
Vertinary Raw Materials
Type of Product
Auxiliaries and Other Medicinal Chemicals
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Trademark
Henrikang
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Tetramisole HCl
Origin
Shaanxi China
                   Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

 
   Factory Supply CAS 78628-80-5 Terbinafine HCl Powder
 
Product NameFactory Supply CAS 78628-80-5 Terbinafine HCl Powder
CAS78628-80-5
AppearanceWhite Crystalline Powder
Molecular formulaC21H25N
Molecular Weight327.9
Assay98%
Shelf Life24 months when properly stored
StorageKeep in a cool, dry, dark location
 
Factory Supply CAS 78628-80-5 Terbinafine HCl PowderWhat is Terbinafine HCL?

Terbinafine HCL a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Terbinafine·HCl a member of the allylamine class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis. Additionally, Terbinafine has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed.

 

Function of Terbinafine HCL

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.


 
Application of Terbinafine HCL 

1. Terbinafine HCL is mainly effective on the dermatophyte group of fungi.

2. As a 1% cream or powder, Terbinafine HCL is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.

3. Oral 250mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied. 

4.Terbinafine HCLmay induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.

 

Product NameCAS No.Product NameCAS No.
Lufenuron103055-07-8Toltrazuril69004-03-1
Nitenpyram120738-89-8Praziquantel/Biltricide55268-74-1
Fenbendazole43210-67-9Tetramisole Hcl5086-74-8
Levamisole14769-73-4Ponazuril9004-4-2
Diclazuril101831-37-2Florfenicol73231-34-2
Ivermectin70288-86-7Enrofloxacin Hcl112732-17-9
Albendazole54965-21-8Mebendazole31431-39-7

Company Information
Factory Supply CAS 78628-80-5 Terbinafine HCl Powder
Factory Supply CAS 78628-80-5 Terbinafine HCl Powder


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Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

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Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

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Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

Factory Supply CAS 78628-80-5 Terbinafine HCl Powder

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Factory Supply CAS 78628-80-5 Terbinafine HCl Powder
Factory Supply CAS 78628-80-5 Terbinafine HCl Powder
 

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