Application:

While ezetimibe reduces LDL cholesterol, it has not been shown to have an impact on outcomes such as risk of death or major cardiovascular event like heart attack or stroke. Its effectiveness in reducing atherosclerosis in clinical trials has been inconsistent. The question of whether ezetimibe could make a difference in major outcomes was examined in the IMPROVE-IT trial, which compared treatment with ezetimibe vs. placebo on top of a background regimen of statin therapy in people who have had recent episodes of acute coronary syndrome over a six-year period. The trial results showing that ezetimibe treatment lowered the risk of experiencing a vascular event by 2%.

Ezetimibe Function:

1) Ezetimibe reduces the amount of cholesterol absorbed by the body.
2) Ezetimibe is used to treat high cholesterol.
3) Ezetimibe is sometimes given with other cholesterol-lowering medications.