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Product name: Amitriptyline
Synonyms: Amitriptyline Hydrochloride
Cas No.: 549-18-8
Specification: USP41
Molecular Formula: C20H24ClN
Molecular Weight: 313.864
Appearance and character: White to off-white powder
Melting Point: 11 °C
Usage:
Amitriptyline Hydrochloride is an antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
Amitriptyline is used in ankylosing spondylitis for pain relief as a preventive for patients with frequent/chronic migraines. It is also used as a preventive for patients with recurring biliary dyskinesia (sphincter of Oddi dysfunction) Amitriptyline is also used in the treatment of nocturnal enuresis in children.
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