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High Quaity Chemical API Topiroxostat with Good Price CAS 577778 -58-6

China High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6, Find details about China Topiroxostat, Fyx 051 from High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6

Model NO.
Topiroxostat
CAS
577778-58-6
Appearance
White Powder
Usage
Chemical Raw material
Shelf Life
2 Years
Delivery Time
7-10 Days
Storage
Cool and Dry Place
Mf
C13h8n6
Trademark
BIOCAR
Transport Package
Bag and Drum
Specification
kg
Origin
China
HS Code
2934999090
Model NO.
Topiroxostat
CAS
577778-58-6
Appearance
White Powder
Usage
Chemical Raw material
Shelf Life
2 Years
Delivery Time
7-10 Days
Storage
Cool and Dry Place
Mf
C13h8n6
Trademark
BIOCAR
Transport Package
Bag and Drum
Specification
kg
Origin
China
HS Code
2934999090
high  quaity  chemical API Topiroxostat  with good price  cas   577778-58-6

 High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6
 

Basic Info

Chemical Name4-(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile
Synonyms

4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile;4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-2-Pyridinecarbonitrile;Topiroxostat;Topiroxostat [INN];Uriadec (TN);Expand

CAS No.577778-58-6
Molecular FormulaC13H8N6
Molecular Weight248.24300
PSA91.14000
LogP1.80038

High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6

What is Topiroxostat?

Topiroxostat is an inhibitor of xanthine oxidoreductase (IC50 = 5.3 nM), an enzyme that converts xanthine to urate. Formulations containing topiroxostat are effective in vivo, lowering urate levels in the serum of patients with hyperuricemia. In rats, but not primates, topiroxostat treatment results in the formation of xanthine crystals, resulting in nephritis. Topiroxostat also inhibits ATP-binding cassette transporter G2 (ABCG2; IC50 = 0.18 μM), a high-capacity urate transporter that functions in both renal and extrarenal urate secretion.

 
Batch No.HF171121Quantity8.5kgs
Mfg. DateNov. 21, 2017PackageAs required
Rep. DateNov. 25, 2017Exp. DateNov. 20, 2019
ItemsStandardsResults
AppearanceWhite or off-white solid powderComplies
IdentificationBy IRComplies
By HPLCComplies
SolubilitySoluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in waterComplies
Polymorphic FormPolymorphic form 1Complies
Melting Point211ºC~216ºC212.8ºC~214.9ºC
Water Content≤ 0.50%0.10%
Heavy Metals≤ 20ppmComplies
Residue on Ignition≤ 0.20%0.09%
Related SubstanceAny single impurity: ≤0.10%0.06%
Total Impurities: ≤1.00%0.16%
Assay                  (on the anhydrous basis)98.0%~102.0%99.94%
Particle SizeD90: ≤100µmComplies
Reference StandardIn-house Standard
ConclusionThe product complied to In-house standard.
StoragePreserve in tight,light-resistant containers in a cool place


High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6

1.What are your prices?
A1:Our prices are subject to change depending on supply and other market factors. We will send you an updated price list after your company contact us for further information.
2.Can you supply the relevant documentation?
A2:Yes, we can provide most documentation including Certificates of Analysis / Conformance; Insurance; Origin, and other export documents where required.
3.How about the quality of your products?
A3:We take quality as our life. We control the quality in every process strictly and we had founded a quite rounded quality control system. We promise to bring 100% best quality products to consumers.
4.What's your MOQ (Minimum Order Quantity)?
A4: Our MOQ is 1 kg.(If you need less, please communicate with us)
5.Is it possible to provide samples?
A5:Of course,we provide samples for free but you need to bear the freight.
6.How much does shipping cost?
A6:Shipping costs vary according to the shipping method and your ship-to country.You can tell me your country and the mode of transportation, we will give you the price of the shipping cost at the first time.

High Quaity Chemical API Topiroxostat with Good Price CAS 577778-58-6
 

Shipping Advise

1. By Express 
------Suitable for under 50kg, Fast:3-7 days.
High cost; Door to door service. Easy to pick up the goods.
2. By Air 
------Suitable for more than 50 kg, Fast:3-7 days,
High cost, airport to airport. professional broker needed.
3. By sea
------Suitable for more than 500kg. Slow: 5-45 days,
Low cost. Port to Port, professional broker needed.


Packaging Details:
1-5kg Aluminium Foiled Bag and  Bag Packed with Aluminium Foiled Bag with  Bag inside .
5-20kg Carton, 25kg Paper Drum Packed with Paper drum with Double Plastic Bags inside
Shelf Life: 2 years, Keep in cool and dry place

 

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