Metformin is the first-line medication for the treatment of type 2 diabetes.This is particularly true in people who are overweight. It is also used in the treatment of polycystic ovary syndrome.Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.It is not associated with weight gain.It is taken by mouth.     

For mild diabetes. It is mainly used for non-insulin-dependent diabetes mellitus, in which obese patients can be used as the drug of choice, and insulin-dependent diabetes mellitus can also be used in combination with insulin. It is effective in cases where certain sulfonylureas are ineffective.

This product is a biguanide oral hypoglycemic agent. It has a variety of mechanisms of action, including delaying the uptake of glucose from the gastrointestinal tract, increasing the utilization of peripheral glucose by increasing the sensitivity of insulin, and inhibiting excessive gluconeogenesis of the liver and kidney. This product does not reduce blood sugar levels in non-diabetic patients. During the patient's medication, the body weight is usually reduced, plasma cholesterol, triglyceride and pre-beta lipoprotein levels are reduced, and peripheral glucose metabolism can be improved.

Fuction&Application of Metformin

1. Increase the sensibility of surrounding tissues to insulin and the insulin-mediated usage of amylaceum.

2. Increase the the amylaceum usage to those organization which are not dependant on insulin, such as brain, blood corpuscle, medulla renis, intestinal tract, skin and so on.

3.  Restrain the heteroplasia of hepatic glycogen, lower the output of hepatic glycogen.

4. Restrain the intestinal wall cells from absorbing amylaceum.

5. Restrain the biosynthesis and storage of cholesterol, lower triglyceride, and total level of cholesterol.

Different from the function of insulin, it has no effect on promoting the combination of fat, no evident action of regulating blood sugar level to those who are normal, it usually causes no hypoglycemia action when used as the only medicine to II Diabetes.