API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

China API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate, Find details about China Pimavanserin Tartrate, Pimavanserin Tartrate Powder from API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Model NO.
Condavo-Pimavanserin Tartrate
Name
Pimavanserin Tartrate
Product Name
Pimavanserin Tartrate Powder
Other Name
Bvf-048
Appearance
White Powder
Color
White Color
Test Method
HPLC UV
Storage
Cool Dry Place
Shelf Life
2 Years
Assay
99%
Grade
Medicine Grade
COA
Available
CAS
706782-28-7
Mf
C54h74f2n6o10
MW
1005.2
Function
Antidepressant
Trademark
Condavo
Transport Package
1kg/ Aluminium Bag or 25kg/Drum; as Required
Specification
99%
Origin
Shaanxi
Model NO.
Condavo-Pimavanserin Tartrate
Name
Pimavanserin Tartrate
Product Name
Pimavanserin Tartrate Powder
Other Name
Bvf-048
Appearance
White Powder
Color
White Color
Test Method
HPLC UV
Storage
Cool Dry Place
Shelf Life
2 Years
Assay
99%
Grade
Medicine Grade
COA
Available
CAS
706782-28-7
Mf
C54h74f2n6o10
MW
1005.2
Function
Antidepressant
Trademark
Condavo
Transport Package
1kg/ Aluminium Bag or 25kg/Drum; as Required
Specification
99%
Origin
Shaanxi
API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate
API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate powder Pimavanserin Tartrate
Product Description

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin TartrateAPI Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Product NamePimavanserin Tartrate
CAS706782-28-7
AppearanceWhite crystalline powder
MFC54H74F2N6O10
MW1005.2
Purity99%
Shelf Life2 Years

The phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

Sample Display

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Function & Application

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin TartratePimavanserin is the active pharmaceutical ingredient of Nuplazid®, which was approved by the FDA in 2016 for the treatment of hallucinations and delusions associated with psychosis in patients suffering from Parkinson's disease.
API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Pimavanserin is the active pharmaceutical ingredient of Nuplazid®, which was approved by the FDA in 2016 for the treatment of hallucinations and delusions associated with psychosis in patients suffering from Parkinson's disease. Its exact mechanism of action is unclear. The drug exhibits a combination of inverse agonist and antagonist activity at the serotonin 2A receptors (5-HT2A) and, to a lesser extent, at the 5-HT2C receptors in the central nervous system, which is believed to contribute to its antipsychotic activity. Pimavanserin is absorbed in the gastrointestinal tract and is highly bound to plasma protein (approximately 95%). Following the administration of a single 34-mg dose of pimavanserin, the time to maximum plasma concentration is six hours, the half-life is approximately 57 h and the mean (standard deviation, SD) apparent volume of distribution is 2,173 (307) L. Pimavanserin is metabolized in the liver predominantly by cytochrome P450 (CYP3A4 and CYP3A5) and does not cause significant CYP3A4 inhibition or induction. It has a major active N-desmethylated metabolite AC-279, whose half-life is 200 h.
Specification

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin TartrateAPI Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Packaging & Shipping

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Certifications

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

Our Team

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate

About Us

API Antidepressant Pimavanserin Tartrate Material Pimavanserin Tartrate Powder Pimavanserin Tartrate