China Fast Delivery Clindamycin Phosphate CAS 24729-96-2, Find details about China Active Pharmaceutical Ingredients, Biochemistry from Fast Delivery Clindamycin Phosphate CAS 24729-96-2
Product Name: | Clindamycin phosphate |
Structural Formula: | ![]() |
CAS: | 24729-96-2 |
Chemical Name: | Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-a-D-galacto-octopyranoside 2-(dihydrogen phosphate) |
MF: | C18H34ClN2O8PS |
MW: | 505 |
EINECS: | 246-433-0 |
Property: | White or almost white powder, slightly hygroscopic,freely soluble in water, very slightly soluble in alcohol, practically insoluble in ether and methylene chloride. |
Package: | 25KG/Drum |
Storage: | Sealed and preserved in tight container |
Product Categories: | Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);API's;Intermediates & Fine Chemicals;Pharmaceuticals |
Chemical Properties
Melting point | 114 °C |
Boiling point | 159°C |
Refractive index | 122 ° (C=1, H2O) |
Solubility | DMSO: soluble224mg/mL at 25°C |
Form | Solid |
pka | pKa 0.964±0.06 (H2O t=21) (Uncertain);6.06 ±0.06 (I=0.008)(H2O t=21) (Uncertain) |
Water Solubility | Freely soluble in water |
Merck | 14,2356 |
Stability: | Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins. |
Uses | Lincosamide antibacterial. |
Uses | Clindamycin impurity in bulk drug. |
Uses | A highly water soluble Clindamycin prodrug. |
Uses | Clindamycin 2-phosphate is a a salt of clincamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. |
Uses | Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. |
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
Certification