Anti-Cancer Everolimus API Everolimus Powder Raw Powder Everolimus
China Anti-Cancer Everolimus API Everolimus Powder Raw Powder Everolimus, Find details about China Everolimus, Supply Everolimus from Anti-Cancer Everolimus API Everolimus Powder Raw Powder Everolimus
Basic Info.
Model NO.
D-sung Everolimus
Product Name
Everolimus
Name
Everolimus Powder
Appearance
White Powder
Grade
Pharmaceutical Grade
Color
White
Assay
HPLC 99%
Application
Pharmaceutical;Immunosuppressant
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
159351-69-6
Mf
C53h83no14
MW
958.24
Density
1.18
Boiling Point
998.7 °c at 760 Mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Model NO.
D-sung Everolimus
Product Name
Everolimus
Name
Everolimus Powder
Appearance
White Powder
Grade
Pharmaceutical Grade
Color
White
Assay
HPLC 99%
Application
Pharmaceutical;Immunosuppressant
Specific
COA
Test Method
HPLC
Shelf Life
2 Years
CAS No.
159351-69-6
Mf
C53h83no14
MW
958.24
Density
1.18
Boiling Point
998.7 °c at 760 Mmhg
Trademark
D-sung
Transport Package
Negotiable
Specification
99%
Origin
Shaanxi Xi′an
Product Desciption
Anti-Cancer Everolimus API Everolimus Powder Raw Powder Everolimus
| Product name | Everolimus |
| Cas number | 159351-69-6 |
| Appearance | White powder |
| MF | C53H83NO14 |
| MW | 958.24 |
Everolimus, an orally adminstered rapamycin analog, has recently been approved by the FDA for treatment of renal cell carcinoma (RCC) refractory to inhibitors of vascular endothelial growth factor (VEGF) receptor signaling. Everolimus significantly increased progression-free survival (median PFS for the everolimus treated group was 4.0 months versus 1.9 months for the placebo group), although tumor regressions were observed only infrequently. While the target for everolimus, (the serine/threonine kinase mTOR) is well established, the mechanism by which this agent retards tumor growth is not well defined. Further, biomarkers that predict tumor sensitivity are still elusive. The mechanism of action, preclinical antitumor activity, and clinical activity of everolimus against RCC are reviewed.
Everolimus is a medication used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
Everolimus is a macrolide derived from rapamycin (sc-3504) with immunosuppressant properties shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Studies indicate that everolimus is a mTOR (FRAP) inhibitor that displays high affinity toward the intracellular receptor FKBP12. Additionally, the Everolimus-FKBP12 complex decreases the activity of the S6K1 and 4EBP by binding to FRAP.
Everolimus, an orally adminstered rapamycin analog, has recently been approved by the FDA for treatment of renal cell carcinoma (RCC) refractory to inhibitors of vascular endothelial growth factor receptor signaling. Everolimus significantly increased progression-free survival (median PFS for the everolimus treated group was 4.0 months versus 1.9 months for the placebo group), although tumor regressions were observed only infrequently. While the target for everolimus, (the serine/threonine kinase mTOR) is well established, the mechanism by which this agent retards tumor growth is not well defined. Further, biomarkers that predict tumor sensitivity are still elusive. The mechanism of action, preclinical antitumor activity, and clinical activity of everolimus against RCC are reviewed.
Everolimus is a medication used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
Everolimus is a medication used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
Everolimus is a macrolide derived from rapamycin (sc-3504) with immunosuppressant properties shown to inhibit cell proliferation induced by growth factors. Macrolides belong to a group of antibiotics that bind to the 50S ribosomal subunit and inhibit protein synthesis. Studies indicate that everolimus is a mTOR (FRAP) inhibitor that displays high affinity toward the intracellular receptor FKBP12. Additionally, the Everolimus-FKBP12 complex decreases the activity of the S6K1 and 4EBP by binding to FRAP.
Everolimus, an orally adminstered rapamycin analog, has recently been approved by the FDA for treatment of renal cell carcinoma (RCC) refractory to inhibitors of vascular endothelial growth factor receptor signaling. Everolimus significantly increased progression-free survival (median PFS for the everolimus treated group was 4.0 months versus 1.9 months for the placebo group), although tumor regressions were observed only infrequently. While the target for everolimus, (the serine/threonine kinase mTOR) is well established, the mechanism by which this agent retards tumor growth is not well defined. Further, biomarkers that predict tumor sensitivity are still elusive. The mechanism of action, preclinical antitumor activity, and clinical activity of everolimus against RCC are reviewed. Everolimus is a medication used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.
You Might Also Like
Mfr Rate Index Plastic Melt Flow Analyzer Test Testing Equip......
Metal CNC Plasma Cutting Machine for 3-35mm Iron, Steel Cutt......
Precast Concrete Threaded Waved Lifting Wavy Tail Anchor
Bateria Litio E-Bike Battery 48V 12.5ah Replacement in Frame......
High Quality Gym Fitness Medical Salon Equipment Abdominal S......
Black Red Good Racing Office Seat Gaming Chairs
LED Large Outdoor Christmas Ornaments Balls Giant 3D Motif L......
Multi Functional Gym Equipment 45 Angled Leg Press & Hack Sl......
UV Aging Test Chamber for Products Accelerate Aging Test
Copper Clad Laminate Use Al2O3 Top Quality Spherical Aluminu......
Medical ECG Electrocardiograph Device 12 Channel Sun-8121
Equivalent to Nomex Fire Retardant Coverall