Lincomycin 10% Injection Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use

China Lincomycin 10% Injection Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use, Find details about China Lincomycin Hydrochloride, Antibiotic from Lincomycin 10% Injection Veterinary Medicine Drug for Cattle Sheep Goats Horse Poultry Use

Basic Info.

Model NO.

Injection

Trademark

JIUDING

Transport Package

Carton

Specification

10%, 10ml/50ml/100ml

Origin

China

HS Code

3004909099

Model NO.

Injection

Trademark

JIUDING

Transport Package

Carton

Specification

10%, 10ml/50ml/100ml

Origin

China

HS Code

3004909099

Product Desciption

Lincomycin 10% Injection
FOR VETERINARY USE ONLY

COMPOSITION:
Lincomycin Hydrochloride.........................100mg
Solvents add to.............................................1ml
DESCRIPTION:
This product is a colorless or almost colorless clear liquid.
PHARMACOLOGICAL ACTIONS:
Pharmacodynamics Lincomycin belongs to the lincosamide class of antibacterial drugs and is a bacteriostatic agent. Sensitive bacteria include Staphylococcus aureus (including penicillin-resistant strains), Streptococcus, pneumococcus, Bacillus anthracis, Erysipelas suis, and certain mycoplasma (Mycoplasma hyopneumoniae, Mycoplasma hyorhinis, Mycoplasma swine joint fluid), Leptospira and anaerobic bacteria (such as Fusobacterium, Clostridium tetani, Clostridium perfringens and Most actinomycetes, etc.). It mainly acts on the 50S subunit of the bacterial ribosome and exerts an antibacterial effect by inhibiting the elongation of the peptide chain and affecting the synthesis of protein.
Pharmacokinetics After intramuscular injection, the absorption is rapid. A single intramuscular injection in pigs is 11mg/kg, and the peak plasma concentration is 6.25ug/ml. The plasma protein binding rate is 57% to 72%. It is widely distributed in the body, and its apparent volume of distribution in pigs is 2.8L/kg. It can reach effective levels in most tissues, pleural fluid, ascites, and joint fluid. The concentration is particularly high in bone tissue, but it cannot enter the cerebrospinal fluid through the blood-brain barrier. Through Placenta and distribution into breast milk. It is mainly metabolized in the liver, excreted in bile and feces, and a small amount is excreted in urine.
INDICATIONS:
Used for gram-positive bacterial infections, especially penicillin-resistant bacterial infections that are sensitive to this product, such as staphylococcal disease, streptococcal disease, mastitis, etc., and can also be used for swine pancreatic disease and mycoplasma infection caused by swine asthma .
DOSAGE AND ADMINISTRATION:
Intramuscular injection: One dose, per 1kg body weight, 0.1ml for pigs, once a day; 0.1ml for dogs and cats, twice a day, for 3 to 5 days.
DRUG INTERACTIONS:
(1) When combined with gentamicin, it has a synergistic effect on gram-positive bacteria such as staphylococcus and streptococcus.
(2) Combined use with aminoglycoside and peptide antibiotics may enhance the blocking effect on neuromuscular junctions. Combined with erythromycin, it has an antagonistic effect, because the site of action is the same, and the affinity of erythromycin to the 50S subunit of the bacterial ribosome is stronger than this product.
(3) It should not be combined with antidiarrheal drugs that inhibit intestinal peristalsis and contain kaolin.
(4) There are contraindications to compatibility with kanamycin and novobiocin.
ADVERSE REACTIONS:
Has neuromuscular blocking effect.
WARNINGS:
Intramuscular injection may cause transient diarrhea or soft stools. Although it is rare, necessary measures should be taken to prevent dehydration if it occurs.
WITHDRAWAL PERIODS:
Pigs: 2 days.
STORAGE:
Sealed and Store below 30ºC. Protected from light.
PACKAGE: 10ml, 50ml, 100ml.
SHELF LIFE: 3 years.
Shelf life after opening: 28 days.

KEEP OUT OF THE REACH OF CHILDREN.

MANUFACTURED BY:
SHIJIAZHUANG JIUDING ANIMAL PHARMACEUTICAL CO., LTD

About Us