Supplement Nicotinamide Adenine Dinucleotide Powder CAS 53-84-9 Nad Nad+ Nadh Nadp+ Nadph Nmn

China Supplement Nicotinamide Adenine Dinucleotide Powder CAS 53-84-9 Nad Nad+ Nadh Nadp+ Nadph Nmn, Find details about China Nad Powder, Nad+ from Supplement Nicotinamide Adenine Dinucleotide Powder CAS 53-84-9 Nad Nad+ Nadh Nadp+ Nadph Nmn

Basic Info.

Model NO.

top quality

CAS No.

N/a

Einecs No.

N/a

Appearance

White Powder

MOQ

100g

Storge

2-8 Degree

Exp.

24 Months

Trademark

senwayer

Transport Package

Per Bag

Specification

1KG

Origin

China

HS Code

2601111000

Model NO.

top quality

CAS No.

N/a

Einecs No.

N/a

Appearance

White Powder

MOQ

100g

Storge

2-8 Degree

Exp.

24 Months

Trademark

senwayer

Transport Package

Per Bag

Specification

1KG

Origin

China

HS Code

2601111000

Product Desciption

supplement Nicotinamide adenine dinucleotide powder CAS 53-84-9 NAD NAD+/NADH,NADP+/NADPH/NMN

Physical Characters and specifications

Product name	beta-Nicotinamide adenine dinucleotide
CAS No.	53-84-9
Other Names	NAD
Molecular Formula	C21H27N7O14P2
Molecular weight	663.43
EINECS NO.	200-184-4
Grade Standard	Medicine Grade
COA	Avaliable

Item	Specifications
Appearance	White powder.
Purity	95%, 98%, 99%
Melting point	140 - 142ºC
Specific rotation	D20 -31.5
PH	~3.0 (50mg/mL in water)
Solubility	H2O: 50 mg/mL
Storage condition	-20ºC
Shelf life	3 years

Product Introduction

Nicotinamide adenine dinucleotide ( NAD ) is a coenzyme found in all living cells. The compound is a dinucleotide, because it consists of two nucleotides joined through theirphosphate groups. One nucleotide contains an adenine base and the other nicotinamide. Nicotinamide adenine dinucleotide exists in two forms: an oxidized and reduced form abbreviated as NAD+ and NADH respectively.

Nicotinamide Adenine Dinucleotide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.

In addition, Nicotinamide Adenine Dinucleotide has prevention and treatment of heart block, sinus node function and anti fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.

Function

Nicotinamide adenine dinucleotide has several essential roles in metabolism. It acts as acoenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions, as a precursor of the second messenger molecule cyclic ADP-ribose, as well as acting as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. In addition to these metabolic functions, NAD+ emerges as an adenine nucleotide that can be released from cells spontaneously and by regulated mechanisms, and can therefore have important extracellular roles.

The enzymes that make and use NAD+ and NADH are important in both pharmacology and the research into future treatments for disease. Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+biosynthesis.
The coenzyme NAD+ is not itself currently used as a treatment for any disease. However, it is being studied for its potential use in the therapy of neurodegenerative diseases such asAlzheimer's and Parkinson disease. Evidence on the benefit of NAD+ in neurodegeneration is mixed; some studies in mice have produced promising results whereas a placebo-controlled clinical trial in humans failed to show any effect.

NAD+ is also a direct target of the drug isoniazid, which is used in the treatment oftuberculosis, an infection caused by Mycobacterium tuberculosis. Isoniazid is a prodrug and once it has entered the bacteria, it is activated by a peroxidase enzyme, which oxidizes the compound into a free radical form. This radical then reacts with NADH, to produce adducts that are very potent inhibitors of the enzymes enoyl-acyl carrier protein reductase, and dihydrofolate reductase. In one experiment, mice given NAD for one week had improved nuclear-mitochrondrial communication.

1. Nutritional peptides enhance the assimilation of mineral elements.
2. Nucleotides develop nthe immunity and enable animals to produce more IgG and IgM.
3. Nucleotides promote intestinal and bring regeneration of benefical bacteria.
4. Nucleotides accelerate the liver recovery from damages.
5. Mannan oligosaccharides absorb pathogenic bacteria and take them out of bodies.
6. Beta-glucan activate macrophages to improve animal immunity.
7. I+G improve feed palatability and increase the intake