Manufacturer Supply CAS 53-84-9 Nicotinamide Adenine Dinucleotide Powder Nad Nad+ Nadh Nadp+ Nadph Nmn
China Manufacturer Supply CAS 53-84-9 Nicotinamide Adenine Dinucleotide Powder Nad Nad+ Nadh Nadp+ Nadph Nmn, Find details about China Nad+, Nad Injection from Manufacturer Supply CAS 53-84-9 Nicotinamide Adenine Dinucleotide Powder Nad Nad+ Nadh Nadp+ Nadph Nmn
Basic Info.
Model NO.
JL-N
Product Name
Nicotinamide Adenine Dinuclotide/Nad
CAS
53-84-9
Appearance
White Powder
Shipping Origin
China
Shelf Life
2 Years
Coa
Available
Storage
Cool Dried Storage
Package
1kg/Bag 25kg/Drum
Assay
Min 98%
MOQ
10 Gram
Sample
Available
Test Method
HPLC UV
Standard
Export Standard
Trademark
Julong
Transport Package
1kg/Foil Bag, 25 Kg/Drum
Specification
99%min
Origin
China
Model NO.
JL-N
Product Name
Nicotinamide Adenine Dinuclotide/Nad
CAS
53-84-9
Appearance
White Powder
Shipping Origin
China
Shelf Life
2 Years
Coa
Available
Storage
Cool Dried Storage
Package
1kg/Bag 25kg/Drum
Assay
Min 98%
MOQ
10 Gram
Sample
Available
Test Method
HPLC UV
Standard
Export Standard
Trademark
Julong
Transport Package
1kg/Foil Bag, 25 Kg/Drum
Specification
99%min
Origin
China
Product Desciption
Products Description
Nicotinamide adenine dinucleotide has several essential roles in metabolism. It acts as acoenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions, as a precursor of the second messenger molecule cyclic ADP-ribose, as well as acting as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins. In addition to these metabolic functions, NAD+ emerges as an adenine nucleotide that can be released from cells spontaneously and by regulated mechanisms, and can therefore have important extracellular roles.
The enzymes that make and use NAD+ and NADH are important in both pharmacology and the research into future treatments for disease. Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+biosynthesis.
The coenzyme NAD+ is not itself currently used as a treatment for any disease. However, it is being studied for its potential use in the therapy of neurodegenerative diseases such asAlzheimer's and Parkinson disease. Evidence on the benefit of NAD+ in neurodegeneration is mixed; some studies in mice have produced promising results whereas a placebo-controlled clinical trial in humans failed to show any effect.
NAD+ is also a direct target of the drug isoniazid, which is used in the treatment oftuberculosis, an infection caused by Mycobacterium tuberculosis. Isoniazid is a prodrug and once it has entered the bacteria, it is activated by a peroxidase enzyme, which oxidizes the compound into a free radical form. This radical then reacts with NADH, to produce adducts that are very potent inhibitors of the enzymes enoyl-acyl carrier protein reductase, and dihydrofolate reductase. In one experiment, mice given NAD for one week had improved nuclear-mitochrondrial communication.
1. Nutritional peptides enhance the assimilation of mineral elements.
2. Nucleotides develop nthe immunity and enable animals to produce more IgG and IgM.
3. Nucleotides promote intestinal and bring regeneration of benefical bacteria.
4. Nucleotides accelerate the liver recovery from damages.
5. Mannan oligosaccharides absorb pathogenic bacteria and take them out of bodies.
6. Beta-glucan activate macrophages to improve animal immunity.
7. I+G improve feed palatability and increase the intake
1. Diagnostic reagents raw materials, scientific research experiments.
2. Health food, cosmetic, feed additive
3. API production
Specification
Package & Delivery
Payment
Product name | Nad,NAD price,NAD china,NAD Manufacturer,NAD Supplier,NAD Factory |
CAS | 53-84-9 |
| Appearance | White powder |
Molecular formula | C21H27N7O14P2 |
MW | 663.425 |
| Purity | 99% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Nicotinamide adenine dinucleotide (NAD) is a cofactor found in all living cells. The compound is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other nicotinamide. Nicotinamide adenine dinucleotide exists in two forms: an oxidized and reduced form, abbreviated as NAD+ and NADH respectively.
Nicotinamide Adenine Dinucleotide is easy to absorb oral, and can be widely distributed in the body, the excess metabolites or prototype quickly expel from urine. Nicotinamide is part of coenzyme I and coenzyme II, plays the role of hydrogen delivery in biological oxidation respiratory chain, can promote biological oxidation processes and tissue metabolism, maintain normal tissue (especially the skin, digestive tract and nervous system) integrity has an important role.
In addition, Nicotinamide Adenine Dinucleotide has prevention and treatment of heart block, sinus node function and anti fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.
In addition, Nicotinamide Adenine Dinucleotide has prevention and treatment of heart block, sinus node function and anti fast experimental arrhythmias, nicotinamide can significantly improve the heart rate and atrioventricular block caused by verapamil.
Function
The enzymes that make and use NAD+ and NADH are important in both pharmacology and the research into future treatments for disease. Drug design and drug development exploits NAD+ in three ways: as a direct target of drugs, by designing enzyme inhibitors or activators based on its structure that change the activity of NAD-dependent enzymes, and by trying to inhibit NAD+biosynthesis.
The coenzyme NAD+ is not itself currently used as a treatment for any disease. However, it is being studied for its potential use in the therapy of neurodegenerative diseases such asAlzheimer's and Parkinson disease. Evidence on the benefit of NAD+ in neurodegeneration is mixed; some studies in mice have produced promising results whereas a placebo-controlled clinical trial in humans failed to show any effect.
NAD+ is also a direct target of the drug isoniazid, which is used in the treatment oftuberculosis, an infection caused by Mycobacterium tuberculosis. Isoniazid is a prodrug and once it has entered the bacteria, it is activated by a peroxidase enzyme, which oxidizes the compound into a free radical form. This radical then reacts with NADH, to produce adducts that are very potent inhibitors of the enzymes enoyl-acyl carrier protein reductase, and dihydrofolate reductase. In one experiment, mice given NAD for one week had improved nuclear-mitochrondrial communication.
1. Nutritional peptides enhance the assimilation of mineral elements.
2. Nucleotides develop nthe immunity and enable animals to produce more IgG and IgM.
3. Nucleotides promote intestinal and bring regeneration of benefical bacteria.
4. Nucleotides accelerate the liver recovery from damages.
5. Mannan oligosaccharides absorb pathogenic bacteria and take them out of bodies.
6. Beta-glucan activate macrophages to improve animal immunity.
7. I+G improve feed palatability and increase the intake
8. Delay skin aging
Application
1. Diagnostic reagents raw materials, scientific research experiments.
2. Health food, cosmetic, feed additive
3. API production
Specification
Test | Specification | Result |
Appearance | White powder | White powder |
Total heavy metals | <10ppm | <4.966ppm |
Arsenic | <2ppm | <0.50ppm (PQL) |
Lead | <2ppm | 0.086ppm |
Mercury | ||
Cadmium | 0.25ppm (PQL) | |
Water content | <=8% | 5.1% |
Purity | >=98.0% | 98.0% |
Package & Delivery
By Express | By Air | By Sea | ||
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods | Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed | Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed | ||
Payment
Our services
1. All inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
3. OEM/ODM Available.
4. Reasonable & competitive price, fast lead time.
5. Sample is available for your evaluation & Formulation development.
6. Faster delivery:Sample order in stock and 3-7 days for bulk production.
7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 30 Days Warranty of quality of goods.
About us
FAQ
About us
FAQ
Q1.What's your MOQ?
Our MOQ is 10pcs.
Q2: How to contact with us?
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.
Q4:Can you give me a discount price?
A: Sure,it depends on your quantity.
Q5:How can I get a sample?
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.
Q6: How to confirm the Product Quality before placing orders?
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.
Q7:How can I make payment safe?
A: The whole transaction is under Alibaba's (Third party) inspection.
Q8: Is it possible to custom the labels with our own design?
A: Yes, just send us your artworks, you will get what you want.
Our MOQ is 10pcs.
Q2: How to contact with us?
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.
Q3:Which kind of payment terms do you accept?
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.
Q4:Can you give me a discount price?
A: Sure,it depends on your quantity.
Q5:How can I get a sample?
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.
Q6: How to confirm the Product Quality before placing orders?
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.
Q7:How can I make payment safe?
A: The whole transaction is under Alibaba's (Third party) inspection.
Q8: Is it possible to custom the labels with our own design?
A: Yes, just send us your artworks, you will get what you want.
Q9.Can I get the sample?
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).
Q10.Can you accept customized?
Yes,we can according your require to do it.
Q11.How do I place the order?
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).
Q10.Can you accept customized?
Yes,we can according your require to do it.
Q11.How do I place the order?
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.
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