Diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources or derived from the flavonoid hesperidin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

Diosmin differs molecularly from hesperidin by the presence of a double bond between two carbon atoms in diosmin's central carbon ring. Diosmin can be manufactured by extracting hesperidin from citrus rinds, followed by conversion of hesperidin to diosmin. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.

 

Application

1.Diosmin has antioxidant, antiinflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions
2.Diosmin can inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclo-oxygenase.
3.Diosmin can improve the health of capillaries by reducing the capillary permeabilit
4.Diosmin can be used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells.
5.Diosmin can excite the heart and shrink the blood vessel, and then causes the hypertension.
6.To help treat hemorrhoids by reducing swelling (inflammation).
7.To restore normal vein function.

Function

Nature diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums. It is also used to treat swelling of the arms (lymphedema) following breast cancer surgery, and to protect against liver toxicity. It is often taken in combination with hesperidin, another plant chemical.
Diosmin is a yellow to claybank powder.Diosmin is a flavanone glycoside found abundantly in citrus fruits. 
Diosmin is also a potential sedative, possibly acting through opioid or adenosine receptors.Diosmin exhibited pronounced anticancer activity against some selected human carcinoma cell lines.Some in vitro results applied only to the aglycone form.

Specification

Item	Specification	Test Results
Characteristics	Yellow or grey powder and it easy to absorb moisture	Complies
Identification	Positive	Positive
Iodine	≤0.1%	Complies
P yridine	≤200ppm	46ppm
Water(KF)	≤6.0%	4.02%
Sulphated Ash	≤0.3%	0.14%
Paticle Size	90% passes 5μm	Complies
Heavy	≤10ppm	Complies
Total Plate Count	≤1000CFU/g	40CFU/g
Yeast/ Mold	≤100CFU/g	10CFU/g
E.Coli	Negative	Negative
Conclusion	The result conforms the standard

Package & Delivery

By Express		By Air		By Sea
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods		Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed		Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed

 

Payment

Our services

1. All inquiries will be replied within 12 hours. 

2. Dedication to quality, supply & service. 

3. Strictly on selecting raw materials. 

3. OEM/ODM Available. 

4. Reasonable & competitive price, fast lead time.

5. Sample is available for your evaluation & Formulation development. 

6. Faster delivery:Sample order in stock and 3-7 days for bulk production. 

7. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder. 

8. After-Sale Service: 

1) International Authorized Third-Party Test For The Products You Demand. 

2) 30 Days Warranty of quality of goods.

About us

FAQ

Q1.What's your MOQ? 
Our MOQ is 10pcs.

Q2: How to contact with us?
A: Click the Alibaba "Contact Supplier", send us message, you will get reply within 24 hours.

Q3:Which kind of payment terms do you accept?
A: For small order,you can pay on Alibaba by trade assurance. For bulk order, you can pay to our company's bank account.

Q4:Can you give me a discount price?
A: Sure,it depends on your quantity.

Q5:How can I get a sample?
A: You can discuss with us, we normally send sample by FEDEX, DHL,EMS. A few sample is free but you need to pay for the shipping cost.

Q6: How to confirm the Product Quality before placing orders?
A: You can get some sample, or we can send certificate of analysis or HPLC or NMR to you.

Q7:How can I make payment safe?
A: The whole transaction is under Alibaba's (Third party) inspection.

Q8: Is it possible to custom the labels with our own design?
A: Yes, just send us your artworks, you will get what you want.

 

Q9.Can I get the sample?
Yes,we can send you the free sample after received the shipping cost(or you have forwarder,we can send to your forwarder).

Q10.Can you accept customized?
Yes,we can according your require to do it.

Q11.How do I place the order?
Don't worry, we are the gold supplier on Alibaba,and support Trade Assurance,after confirm the details, we will send you the payment link.